Evidence map›Paper›PMID 36798133›Full record

ArticleFrontiers in immunology2023

A novel, non-neuronal acetylcholinesterase of schistosome parasites is essential for definitive host infection.

Patrick J Skelly, Akram A Da'dara

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Comprehensive Mapping of Immune Nanobody Repertoires with NanoMAP.bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Expression, Characterization and Selective Chemical Inhibition of EssentialInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Identification of freshwater snail species and survey of their trematode infections in Ordos, China.International journal for parasitology. Parasites and wildlife · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Patrick J SkellyMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, United States.
Akram A Da'daraMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, United States.
Tufts University · US

Funding

Tegumental acetylcholinesterase as a therapeutic target for schistosomiasisR21AI137667 · NIAID · TUFTS UNIVERSITY BOSTON · PI SKELLY, PATRICK J · 2018 to 2019
$454k
NIAID NIH HHS R21 AI137667
6 · The paper itself

Abstract

Schistosomes are long-lived parasitic worms that infect >200 million people globally. The intravascular life stages are known to display acetylcholinesterase (AChE) activity internally as well as, somewhat surprisingly, on external tegumental membranes. Originally it was hypothesized that a single gene (SmAChE1 in

Indexed as

ParasitesSchistosomiasisAcetylcholinesteraseAnimalsMiceRNA InterferenceSchistosoma mansoniAcetylcholinesteraseacetylcholinesterasehost-parasite interactionnon-neuronalschistosomategument

Identifiers

PMID36798133
PMCPMC9927205
OpenAlexW4318592251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.