Evidence map›Paper›PMID 36797776›Full record

ReviewJournal of biological engineering2023

Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease.

Xinyue Chen, Wenlu Yu, Jing Zhang, Xiao Fan, Xiao Liu, Qi Liu, Su Pan, Richard A F Dixon, Pengyang Li, Peng Yu and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biological engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Xinyue ChenThe Second Clinical Medical College of Nanchang University, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Wenlu YuSchool of Ophthalmology and Optometry of Nanchang University, Nanchang, 330006, China.
Jing ZhangDepartment of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Xiao FanDepartment of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Xiao LiuDepartment of Cardiovascular Medicine, The Second Affiliated Hospital of Sun Yat Sen University, Guangzhou, 51000, Guangdong, China.
Qi LiuWafic Said Molecular Cardiology Research Laboratory, The Texas Heart Institute, Houston, TX, USA.
Su PanWafic Said Molecular Cardiology Research Laboratory, The Texas Heart Institute, Houston, TX, USA.
Richard A F DixonWafic Said Molecular Cardiology Research Laboratory, The Texas Heart Institute, Houston, TX, USA.
Pengyang LiDivision of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA.
Peng YuThe Second Clinical Medical College of Nanchang University, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. yu8220182@163.com.
Ao ShiSchool of Medicine, St. George University of London, London, UK. m1701040@sgul.ac.uk.
Second Affiliated Hospital of Nanchang University · CNNanchang University · CNSt George's, University of London · GBSun Yat-sen University · CNVirginia Commonwealth University · US

Funding

Natural Science Foundation in Jiangxi Province 20192ACBL21037Natural Science Foundation in Jiangxi Province 202002BAB216022
6 · The paper itself

Abstract

Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoration of perfusion. However, current treatments cannot satisfy the need for vascular regeneration to restore blood circulation. As biomedical research has evolved rapidly, a variety of potential alternative therapeutics has been explored widely, such as growth factor-based therapy, cell-based therapy, and material-based therapy including nanomedicine and biomaterials. This review will comprehensively describe the main pathogenesis of vascular injury in ischemic vascular disease, the therapeutic function of the above three treatment strategies, the corresponding potential challenges, and future research directions.

Indexed as

Biological therapyIschemic vascular diseaseTherapeutic angiogenesisTissue revascularization

Identifiers

PMID36797776
PMCPMC9936669
OpenAlexW4321077879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.