Evidence map›Paper›PMID 36797698›Full record

ArticleBMC ophthalmology2023

OCTA biomarkers in adults aged 50 and above: a prospective and cross-sectional community-based study.

Yan Kiu Li, Nicholas Siu-Kay Fung, Jonathan C H Chan, Bonnie N K Choy, Loraine L W Chow, Kendrick C Shih, Jasper K W Wong, Ian Y H Wong

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yan Kiu LiLKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Nicholas Siu-Kay FungDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Pokfulam, Hong Kong, China. vitreoretinal@hku.hk.
Jonathan C H ChanDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Pokfulam, Hong Kong, China.
Bonnie N K ChoyDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Pokfulam, Hong Kong, China.
Loraine L W ChowDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Pokfulam, Hong Kong, China.
Kendrick C ShihDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Pokfulam, Hong Kong, China.
Jasper K W WongDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Pokfulam, Hong Kong, China.
Ian Y H WongDepartment of Ophthalmology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong.
University of Hong Kong · HKCyberport · CNHong Kong Sanatorium and Hospital · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsTo assess the normative values and parameters of optical coherence tomography angiography (OCTA) influencing the best corrected visual acuity (BCVA) in adults aged 50 and above.

methodsThis was a prospective cross-sectional study from an eye screening programme in Hong Kong for 4188 citizens aged 50 and above. Images were analysed using a validated quantification software calculating vessel density and capillary perfusion density (CPD), along with other OCTA parameters, such as the foveal avascular zone area (FAZ) and circularity. OCTA data was collected from May 2019 to December 2020, including a total of 4188 healthy eyes from 4188 subjects.

resultsMean superficial vessel density (MSVD) was 14.48 ± 3.60 mm

conclusionHigh FAZ area and low FAZ circularity, low MSVD in the outer ring, specifically the nasal and temporal outer quadrants, and low MCPD in the outer superior quadrant can be used as biomarkers in predicting a low visual acuity in adults aged 50 and above.

Indexed as

Macula LuteaRetinal VesselsAdultBiomarkersCross-Sectional StudiesFemaleFluorescein AngiographyFundus OculiHumansMaleProspective StudiesTomography, Optical CoherenceBiomarkersEpidemiologyMaculaOCTAVision

Identifiers

PMID36797698
PMCPMC9936659
OpenAlexW4321110286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.