Evidence map›Paper›PMID 36797424›Full record

ArticleIntensive care medicine experimental2023

Precision of CT-derived alveolar recruitment assessed by human observers and a machine learning algorithm in moderate and severe ARDS.

Ludmilla Penarrubia, Aude Verstraete, Maciej Orkisz, Eduardo Davila, Loic Boussel, Hodane Yonis, Mehdi Mezidi, Francois Dhelft, William Danjou, Alwin Bazzani and 7 more

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Observational
  3. Observational
  4. Article
  5. Lung Imaging and Artificial Intelligence in ARDS.Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ludmilla Penarrubia *Université Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France.
Aude Verstraete *Service de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
Maciej OrkiszUniversité Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France.
Eduardo DavilaUniversité Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France.
Loic BousselUniversité Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France.
Hodane YonisService de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
Mehdi MezidiService de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
Francois DhelftService de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
William DanjouService de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
Alwin BazzaniService de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
Florian SigaudService de Médecine-Intensive Réanimation, CHU Grenoble-Alpes, Grenoble, France.
Sam BayatSynchrotron Radiation for Biomedicine Laboratory (STROBE), INSERM UA07, Univ. Grenoble Alpes, Grenoble, France.
Nicolas TerziMaladies Infectieuses et Réanimation Médicale, CHU Rennes, Rennes, France.
Mehdi GirardService de Médecine Intensive Réanimation, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 103 Grande Rue de La Croix Rousse, 69004, Lyon, France.
Laurent BitkerUniversité Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France.
Emmanuel RouxUniversité Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France.
Jean-Christophe RichardUniversité Claude Bernard Lyon 1, INSA-Lyon, CNRS, INSERM, CREATIS UMR 5220, U1294, Université de Lyon, Villeurbanne, France. j-christophe.richard@chu-lyon.fr.ORCID http://orcid.org/0000-0003-1503-3035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessing measurement error in alveolar recruitment on computed tomography (CT) is of paramount importance to select a reliable threshold identifying patients with high potential for alveolar recruitment and to rationalize positive end-expiratory pressure (PEEP) setting in acute respiratory distress syndrome (ARDS). The aim of this study was to assess both intra- and inter-observer smallest real difference (SRD) exceeding measurement error of recruitment using both human and machine learning-made lung segmentation (i.e., delineation) on CT. This single-center observational study was performed on adult ARDS patients. CT were acquired at end-expiration and end-inspiration at the PEEP level selected by clinicians, and at end-expiration at PEEP 5 and 15 cmH

resultsThirteen patients were included, of whom 11 (85%) presented a severe ARDS. Intra- and inter-observer measurements of recruitment were virtually unbiased, with 95% confidence intervals (CI

conclusionsThe SRD exceeding intra-observer experimental error in the measurement of alveolar recruitment may be conservatively set to 5% (i.e., the upper value of the CI

Indexed as

Acute respiratory distress syndromeAlveolar recruitmentBiasComputed tomographyMachine learningMeasurement errorRepeatabilityReproducibility

Identifiers

PMID36797424
PMCPMC9934943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.