ArticleScientific reports2023
A mixed-methods study on impact of silicosis on tuberculosis treatment outcomes and need for TB-silicosis collaborative activities in India.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Risk factors for secondary pulmonary hypertension in patients with silicosis.BMC pulmonary medicine · 2026Article
- Article
- [Risk Factors and Prognosis of Pneumoconiosis Combined With Bacterial Pneumonia: Application of a Random Forest Model].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- The Role of Type I Interferons in Tuberculosis and in Tuberculosis-Risk-Associated Comorbidities.Infectious disease reports · 2025Review
- Burden of silicosis based on the Global Burden of Disease Study 2021: trend analysis of incidence, mortality, and disability-adjusted life years, and projections for the next 30 years.Journal of thoracic disease · 2025Article
- Article
- Influences of radiographic silicosis and drug supervisor on the development of multi drug resistant-tuberculosis in West Java, Indonesia.Environmental health and preventive medicine · 2025Article
- Survival analysis shows tuberculosis patients with silicosis experience earlier mortality and need employer-led care models in occupational settings in India.Scientific reports · 2024Article
- Silicosis predicts drug resistance and retreatment among tuberculosis patients in India: a secondary data analysis from Khambhat, Gujarat (2006-2022).BMC pulmonary medicine · 2024Article
- Silicotuberculosis: a critical narrative review.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Treatment Outcomes of Tuberculosis Among Artisanal and Small-Scale Miners in Zimbabwe: A Follow-Up Observational Study Using Secondary Data.International journal of environmental research and public health · 2024Observational
- Framework for implementing collaborative TB-silicosis activities in India: insights from an expert panel.Archives of public health = Archives belges de sante publique · 2024Article
- Mixed methods study on latent tuberculosis among agate stone workers and advocacy for testing silica dust exposed individuals in India.Scientific reports · 2024Article
- The systemic immune-inflammation index is significantly associated with the severity of silicosis: a 9-year retrospective study in Beijing.Frontiers in medicine · 2024Article
- Silicosis as a predictor of tuberculosis mortality and treatment failure and need for incorporation in differentiated TB care models in India.Archives of public health = Archives belges de sante publique · 2023Article
- A Complex Case of Pulmonary Silico-Tuberculosis and Review of Literature.Diagnostics (Basel, Switzerland) · 2023Article
- Challenges and opportunities for silicosis prevention and control: need for a national health program on silicosis in India.Journal of occupational medicine and toxicology (London, England) · 2023Review
- Silicosis, tuberculosis and silica exposure among artisanal and small-scale miners: A systematic review and modelling paper.PLOS global public health · 2023Article
- Challenges in Management of Pulmonary Tuberculosis in Patients with Silicosis.Journal of global infectious diseasesArticle
- Sculpting - A Modern Menace.Indian journal of occupational and environmental medicineArticle
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Abstract
Globally, silicosis and tuberculosis (TB) have been targeted for elimination by 2030. The study's objectives were to determine the association of silicosis with unfavorable TB treatment outcomes, as well as to explore experts' perspectives on improving treatment outcomes among silico-tuberculosis patients. A retrospective cohort study evaluated TB treatment outcomes in Khambhat block, the western part of India, between 138 patients with silico-tuberculosis and 2610 TB patients without silicosis in February-March 2022. 'Unfavorable TB treatment outcomes' was defined as a patient stopping treatment for at least one month, a positive sputum smear at the end of treatment, or, a patient dying while on treatment. During April-July 2022, fifteen in-depth interviews with experts in the field of silicosis/tuberculosis were audio-recorded, transcribed, and analyzed to generate codes (thematic analysis). On multivariable logistic regression analysis, patients with silico-tuberculosis had a 2.3 (95% CI 1.6-3.4) times higher odds of unfavorable treatment outcomes. The experts recommended collaborative TB-silicosis activities for improving treatment outcomes of patients with silico-tuberculosis. I conclude from the study's findings that silicosis is associated with unfavorable TB treatment outcomes in this study setting. All patients with silicosis should be screened for TB and treated according to national TB program guidelines. All patients with TB who have a history of occupational dust exposure should be evaluated for silicosis and provided appropriate pulmonary/vocational rehabilitation.
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