ReviewNPJ microgravity2023
Pathophysiology, risk, diagnosis, and management of venous thrombosis in space: where are we now?
Review in NPJ microgravity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Biological clocks and blood clots in space: circadian disruption-induced modulation of thrombosis risk.Research and practice in thrombosis and haemostasis · 2026Pooled it
- Quantitative Compression Ultrasound via a Force-Area Digital Twin for Mechanistic Assessment of Venous Thrombosis.Annals of biomedical engineering · 2026Article
- Cardiovascular risks and hazards associated with deep space exploration.Communications medicine · 2026Review
- Physical exercise protects cardiovascular fitness in long-term spaceflight: what have we learned?Science China. Life sciences · 2026Review
- Neck-vein thrombosis during spaceflight.British journal of clinical pharmacology · 2026Review
- Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns.British journal of clinical pharmacology · 2026Article
- Integrative focus on the space exposome-integrome: physiological challenges and practical limits of countermeasures beyond low Earth orbit.NPJ microgravity · 2025Review
- Effects of fascial manipulation, vibration exercise, motor imagery, or neuro-muscular electrical stimulation on the coagulation system: A pilot study.Physiological reports · 2025Article
- Jugular venous flow dynamics during acute weightlessness.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Review
- Effects of whole-body vibration or resistive-vibration exercise on blood clotting and related biomarkers: a systematic review.NPJ microgravity · 2023Review
- Retinal venular vessel diameters are smaller during ten days of bed rest.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 19 institutions in 11 countries.
Funding
Abstract
The recent incidental discovery of an asymptomatic venous thrombosis (VT) in the internal jugular vein of an astronaut on the International Space Station prompted a necessary, immediate response from the space medicine community. The European Space Agency formed a topical team to review the pathophysiology, risk and clinical presentation of venous thrombosis and the evaluation of its prevention, diagnosis, mitigation, and management strategies in spaceflight. In this article, we discuss the findings of the ESA VT Topical Team over its 2-year term, report the key gaps as we see them in the above areas which are hindering understanding VT in space. We provide research recommendations in a stepwise manner that build upon existing resources, and highlight the initial steps required to enable further evaluation of this newly identified pertinent medical risk.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.