Evidence map›Paper›PMID 36796830›Full record

ReviewAnatomy & cell biology2023

Novel anatomical guidelines for botulinum neurotoxin injection in the mentalis muscle: a review.

Kyu-Ho Yi, Ji-Hyun Lee, Hye-Won Hu, Hyun-Jun Park, Hyungkyu Bae, Kangwoo Lee, Hee-Jin Kim

Open access · hybridAbstract readReview
In one paragraph

Review in Anatomy & cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Procedural-Based Contemporary Management of Bell's Palsy Long-Term Sequelae: A Narrative Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. SMAS repositioning technique utilizing cog thread: Anatomical perspectives.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  9. Review
  10. Ultrasonographic observations of the paradoxical mentalis bulging in regard to botulinum neurotoxin injection for mentalis muscle.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  11. Article
  12. Review
  13. Consensus Statement on the Use of Botulinum Neurotoxin in the Middle East.Clinical, cosmetic and investigational dermatology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kyu-Ho YiWonju Public Health Center, Wonju, Korea.ORCID https://orcid.org/0000-0001-5572-1364
Ji-Hyun LeeDepartment of Anatomy and Acupoint, College of Korean Medicine, Gachon University, Seongnam, Korea.ORCID https://orcid.org/0000-0003-3732-2698
Hye-Won HuDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0001-5460-6428
Hyun-Jun ParkMaylin Anti-Aging Center Apgujeong, Seoul, Korea.ORCID https://orcid.org/0000-0002-8379-6379
Hyungkyu BaeDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0001-5288-6809
Kangwoo LeeDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0001-8654-8306
Hee-Jin KimDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0002-1139-6261
Yonsei University · KRGachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mentalis muscle is a paired muscle originating from the alveolar bone of the mandible. This muscle is the main target muscle for botulinum neurotoxin (BoNT) injection therapy, which aims to treat cobblestone chin caused by mentalis hyperactivity. However, a lack of knowledge on the anatomy of the mentalis muscle and the properties of BoNT can lead to side effects, such as mouth closure insufficiency and smile asymmetry due to ptosis of the lower lip after BoNT injection procedures. Therefore, we have reviewed the anatomical properties associated with BoNT injection into the mentalis muscle. An up-to-date understanding of the localization of the BoNT injection point according to mandibular anatomy leads to better injection localization into the mentalis muscle. Optimal injection sites have been provided for the mentalis muscle and a proper injection technique has been described. We have suggested optimal injection sites based on the external anatomical landmarks of the mandible. The aim of these guidelines is to maximize the effects of BoNT therapy by minimizing the deleterious effects, which can be very useful in clinical settings.

Indexed as

Botulinum neurotoxinCobblestone chinFacial wrinkleInjection pointMentalis muscle

Identifiers

PMID36796830
PMCPMC10520866
OpenAlexW4321015129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.