ArticleEnvironmental research2023
Exposure to Volatile Organic Compounds Is Associated with Hypertension in Black Adults: The Jackson Heart Study.
Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- Associations between volatile organic compound mixtures and allostatic load: Evidence from the Green Heart Louisville Project.Environmental research · 2026Article
- Plain Language Summarization of Environmental Health Research Using Generative AI: Community-Engaged Qualitative Study.Journal of medical Internet research · 2026Article
- Climate Change and Epidemiology: How Will Environmental Stresses and the Climate Affect Population Health?Circulation. Population health and outcomes · 2026Article
- Exploring the Impact of E‑Waste Exposure on Childhood Blood Pressure: Metabolomics Analysis and Risk Prediction.Environment & health (Washington, D.C.) · 2026Article
- Association of oil spill cleanup-related hydrocarbon exposure with incident hypertension up to 11 years after exposure in the Gulf Long-term Follow-up Study.Environmental health : a global access science source · 2025Article
- Associations of sympathetic activation with exposure to volatile organic compounds: A cross-sectional study.Environmental research · 2025Article
- Occupational Exposure to Ambient Air Pollution: At-Risk Worker Groups, Regulatory and Research Needs An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2025Article
- Blood concentrations of volatile organic compounds and hypertension in the GuLF Study.The Science of the total environment · 2025Article
- Association of oil spill cleanup-related hydrocarbon exposure with hypertension and blood pressure in the Gulf Long-term Follow-up Study.The Science of the total environment · 2025Article
- Exposure to volatile organic compounds and sarcopenia risk in US adults based on NHANES.Scientific reports · 2025Article
- Simultaneous profiling of mercapturic acids, glucuronic acids, and sulfates in human urine.Environment international · 2025Article
- Association Between Volatile Organic Compounds and Circadian Syndrome Among Pre- and Postmenopausal Women.Toxics · 2025Article
- Association between urinary volatile organic compound metabolites and sarcopenia in the US general population: a cross-sectional NHANES study from 2011 to 2018.Scientific reports · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Volatile organic compounds exposure associated with skin cancer among U. S. adults: results from NHANES 2011-2018.Archives of dermatological research · 2025Article
- Clustering analysis of volatile organic compound biomarkers with tobacco exposure and the association with cardiovascular health outcomes in an observation study cohort.Tobacco induced diseases · 2025Article
- Exposure to Volatile Organic Compounds and Blood Pressure in NHANES 2011 to 2018.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Volatile organic compounds exposure in relation to glucose homeostasis and type 2 diabetes in older adults from the NHANES.Scientific reports · 2024Article
- Identifying effects of volatile organic compounds exposure on kidney stone prevalence in U.S. adults: a cross-sectional analysis of NHANES 2007-2020.BMC public health · 2024Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe prevalence of hypertension is higher among Black adults than among White and Hispanic adults. Nevertheless, reasons underlying the higher rates of hypertension in the Black population remain unclear but may relate to exposure to environmental chemicals such as volatile organic compounds (VOCs).
methodsWe evaluated the associations of blood pressure (BP) and hypertension with VOC exposure in non-smokers and smokers in a subgroup of the Jackson Heart Study (JHS), consisting of 778 never smokers and 416 age- and sex-matched current smokers. We measured urinary metabolites of 17 VOCs by mass spectrometry.
resultsAfter adjusting for covariates, we found that amoong non-smokers, metabolites of acrolein and crotonaldehyde were associated with a 1.6 mm Hg (95%CI: 0.4, 2.7; p = 0.007) and a 0.8 mm Hg (95%CI: 0.01, 1.6; p = 0.049) higher systolic BP, and the styrene metabolite was associated with a 0.4 mm Hg (95%CI: 0.09, 0.8, p = 0.02) higher diastolic BP. Current smokers had 2.8 mm Hg (95% CI 0.5, 5.1) higher systolic BP. They were at higher risk of hypertension (relative risk = 1.2; 95% CI, 1.1, 1.4), and had higher urinary levels of several VOC metabolites. Individuals who smoke had higher levels of the urinary metabolites of acrolein, 1,3-butadiene, and crotonaldehyde and were associated with higher systolic BP. The associations were stronger among participants who were <60 years of age and male. Using Bayesian kernel machine regression to assess the effects of multiple VOC exposures, we found that the relationship between VOCs and hypertension among non-smokers was driven primarily by acrolein and styrene in non-smokers, and crotonaldehyde in smokers.
conclusionsHypertension in Black individuals may be attributed, in part, to VOC exposure from the environment or tobacco smoke.
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