Evidence map›Paper›PMID 36796485›Full record

GuidelineJournal of thrombosis and haemostasis : JTH2023

Recommendation on the nomenclature for anticoagulants: updated communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Commitee on the Control of Anticoagulation.

Geoffrey D Barnes, Walter Ageno, Lana A Castellucci, Thita Chiasakul, Renee Eslick, José L Ferreiro, David Gailani, Diana A Gorog, Gregory Y H Lip, Leslie Raffini and 3 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Journal of thrombosis and haemostasis : JTH, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 8 countries.

Geoffrey D BarnesFrankel Cardiovascular Center, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: gbarnes@umich.edu.
Walter AgenoDepartment of Medicine and Surgery, University of Insubria, Varese, Italy.
Lana A CastellucciDepartment of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada. Electronic address: https://twitter.com/LanaCastellucci.
Thita ChiasakulDepartment of Medicine, Research Unit in Translational Hematology, Division of Hematology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand. Electronic address: https://twitter.com/JoyThitaC.
Renee EslickDepartment of Haematology, Canberra Health Services, Garran, Australia. Electronic address: https://twitter.com/Renee_Eslick.
José L FerreiroDepartment of Cardiology, Bellvitge University Hospital, and Bio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), CIBERCV, L'Hospitalet de Llobregat, Spain.
David GailaniVanderbilt University Medical Center, Nashville, Tennessee, USA.
Diana A GorogNational Heart and Lung Institute, Imperial College London, London, UK.
Gregory Y H LipLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, UK; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Leslie RaffiniChildren's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Suely M RezendeDepartment of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Jeffrey I WeitzMcMaster University, Hamilton, Ontario, Canada.
Adam CukerDepartment of Medicine and Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: https://twitter.com/CukerMD.
University of Pennsylvania · USCentro de Investigación en Red en Enfermedades Cardiovasculares · ESChulalongkorn University · THImperial College London · GBMcMaster University · CAUniversidade Federal de Minas Gerais · BRUniversity of Insubria · ITUniversity of Liverpool · GBUniversity of Michigan–Ann Arbor · USUniversity of Ottawa · CAVanderbilt University Medical Center · US

Funding

Biochemistry and Pathophysiology of Factor XI and Contact ActivationR35HL140025 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GAILANI, DAVID · 2018 to 2024
$5.5M
NHLBI NIH HHS R35 HL140025
6 · The paper itself

Abstract

Oral anticoagulation therapy has evolved beyond vitamin K antagonists to include oral direct thrombin inhibitors and factor Xa inhibitors. Collectively known as "direct oral anticoagulants," this class of medications represents the current standard of care for the prevention and treatment of common thrombotic disorders, including atrial fibrillation and venous thromboembolism. Medications that target factors XI/XIa and XII/XIIa are currently under investigation for several thrombotic and nonthrombotic conditions. Given that these emerging medications will likely have distinct risk-benefit profiles to the current direct oral anticoagulants, may have different routes of administration, and could be used for unique clinical conditions (e.g., hereditary angioedema), the International Society on Thrombosis and Haemostasis Subcommittee on Control of Anticoagulation assembled a writing group to make recommendations on the nomenclature of anticoagulant medications. With input from the broader thrombosis community, the writing group recommends that anticoagulant medications be described by the route of administration and specific targets (e.g., oral factor XIa inhibitor).

Indexed as

Atrial FibrillationThrombosisAdministration, OralAnticoagulantsAntithrombinsBlood CoagulationFactor Xa InhibitorsHemostasisHumansAnticoagulantsAntithrombinsFactor Xa Inhibitorsanticoagulantatrial fibrillationfactor Xa inhibitorsfactor XIafactor XIIvenous thromboembolism

Identifiers

PMID36796485
PMCPMC10629847
OpenAlexW4320717322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.