Evidence map›Paper›PMID 36796082›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease.

Samir Rustam, Yang Hu, Seyed Babak Mahjour, Andre F Rendeiro, Hiranmayi Ravichandran, Andreacarola Urso, Frank D'Ovidio, Fernando J Martinez, Nasser K Altorki, Bradley Richmond and 6 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
18.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 76 citations in OpenAlex.

  1. Preclinical models of COPD: a state of the art review.The European respiratory journal · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Progenitor Resilience and the Early Onset of Chronic Lung Diseases: NHLBI workshop report.American journal of respiratory cell and molecular biology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Mucus plugs-associated gene expression identifies pathophysiology shared with chronic bronchitis.American journal of respiratory and critical care medicine · 2026
    Article
  11. Article
  12. Airway epithelial heterogeneity and mucus plugging in asthmatic bronchioles.American journal of respiratory and critical care medicine · 2026
    Article
  13. Article
  14. Cellular plasticity and regenerative mechanisms in the lung.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  15. Targeting the epithelium in pulmonary fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Samir RustamDepartment of Medicine and.
Yang HuCaryl and Israel Englander Institute for Precision Medicine, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York.
Seyed Babak MahjourDepartment of Medicine and.
Andre F RendeiroCaryl and Israel Englander Institute for Precision Medicine, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York.
Hiranmayi RavichandranCaryl and Israel Englander Institute for Precision Medicine, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York.
Andreacarola UrsoDepartment of Surgery, Columbia University Irving Medical Center, New York, New York.
Frank D'OvidioDepartment of Surgery, Columbia University Irving Medical Center, New York, New York.
Fernando J MartinezDepartment of Medicine and.
Nasser K AltorkiDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York.
Bradley RichmondDepartment of Veterans Affairs Medical Center, Nashville, Tennessee.ORCID 0000-0001-6200-5235
Vasiliy PolosukhinDepartment of Veterans Affairs Medical Center, Nashville, Tennessee.
Jonathan A KropskiDepartment of Veterans Affairs Medical Center, Nashville, Tennessee.
Timothy S BlackwellDepartment of Veterans Affairs Medical Center, Nashville, Tennessee.
Scott H RandellMarsico Lung Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Olivier ElementoCaryl and Israel Englander Institute for Precision Medicine, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York.
Renat ShaykhievDepartment of Medicine and.ORCID 0000-0001-8945-548X
Cornell University · USVanderbilt University · USColumbia University Irving Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Martina Gentzsch · 2004 to 2026
$26.5M
Spatiotemporal genomic regulation of disease initiation and progression in pulmonary fibrosisR01HL145372 · NHLBI · TRANSLATIONAL GENOMICS RESEARCH INST · PI Nicholas Eli Banovich, Jonathan Andrew Kropski · 2019 to 2026
$6.0M
The Human Distal Airway Aging ProjectU01HL145561 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHAYKHIEV, RENAT · 2019 to 2022
$2.6M
Defective FGFR2 Signaling in the Small Airway Basal Progenitor Cells in COPDR01HL123544 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHAYKHIEV, RENAT · 2015 to 2019
$2.1M
Amphiregulin-driven COPD-relevant Remodeling of Human Airway EpitheliumR01HL127393 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHAYKHIEV, RENAT · 2016 to 2019
$1.7M
Molecular and Translational Oncology ResearchT32CA203702 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI BLENIS, JOHN, GIANNAKAKOU, PARASKEVI · 2017 to 2021
$1.4M
Mechanisms driving airway inflammation in chronic lung diseaseI01BX002378 · VA · VETERANS HEALTH ADMINISTRATION · PI Timothy S. Blackwell · 2014 to 2026
–
BLRD VA I01 BX002378BLRD VA IK2 BX003841NCI NIH HHS T32 CA203702NHLBI NIH HHS R01 HL123544NHLBI NIH HHS R01 HL127393NHLBI NIH HHS R01 HL145372NHLBI NIH HHS U01 HL145561NIDDK NIH HHS P30 DK065988NIH HHS DK065988NIH HHS R01 HL123544NIH HHS R01 HL127393NIH HHS U01 HL145561
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CD8-Positive T-LymphocytesPulmonary Disease, Chronic ObstructiveBronchiolesDiagnostic ImagingHumansLungbronchioleepitheliumheterogeneityregenerationremodeling

Identifiers

PMID36796082
PMCPMC10161760
OpenAlexW4321018709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.