Evidence map›Paper›PMID 36795651›Full record

ArticleReproduction & fertility2023

Impact of taxane-based chemotherapeutics on male reproductive function.

Charvi Kanodia, Michael P Rimmer, Kathleen Duffin, Rod T Mitchell

Open access · diamondAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproduction & fertility, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Charvi KanodiaEdinburgh Medical School, University of Edinburgh, UK.ORCID 0000-0002-2187-516X
Michael P RimmerMRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UK.ORCID 0000-0002-3295-8753
Kathleen DuffinBiomedical Sciences, University of Edinburgh, UK.ORCID 0000-0003-0039-8525
Rod T MitchellMRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UK.ORCID 0000-0003-4650-3765
MRC Centre for Reproductive Health · GBMedical Research Scotland · GBUniversity of Edinburgh · GB

Funding

Cancer Research UK C157/A25193Medical Research Council MR/N022556/1Medical Research Council MR/S017151/1
6 · The paper itself

Abstract

Lay summary: Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemotherapy drugs, called taxanes, on testicular function and fertility. More studies are needed to aid clinicians in advising patients on how this taxane-based chemotherapy may affect their future fertility.

Indexed as

SemenTaxoidsAnimalsBridged-Ring CompoundsMaleSpermatozoaTestisBridged-Ring CompoundstaxaneTaxoidschemotherapyfertilityfertility preservationpaclitaxeltaxanes

Identifiers

PMID36795651
PMCPMC10083651
OpenAlexW4321004644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.