Evidence map›Paper›PMID 36795468›Full record

ArticleJournal of medical Internet research2023

Deep Learning With Chest Radiographs for Making Prognoses in Patients With COVID-19: Retrospective Cohort Study.

Hyun Woo Lee, Hyun Jun Yang, Hyungjin Kim, Ue-Hwan Kim, Dong Hyun Kim, Soon Ho Yoon, Soo-Youn Ham, Bo Da Nam, Kum Ju Chae, Dabee Lee and 18 more

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Article in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Hyun Woo Lee *Division of Respiratory and Critical Care, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.ORCID 0000-0003-4379-0260
Hyun Jun Yang *College of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-6456-5014
Hyungjin KimCollege of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0003-0722-0033
Ue-Hwan KimAI Graduate School, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.ORCID 0000-0003-2201-2988
Dong Hyun KimCollege of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-3871-7002
Soon Ho YoonCollege of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-3700-0165
Soo-Youn HamDepartment of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-5333-9839
Bo Da NamDepartment of Radiology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-7822-6104
Kum Ju ChaeDepartment of Radiology, Research Institute of Clinical Medicine, Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea.ORCID 0000-0003-3012-3530
Dabee LeeDepartment of Radiology, Dankook University Hospital, Cheonan, Republic of Korea.ORCID 0000-0003-2070-2766
Jin Young YooDepartment of Radiology, Chungbuk National University Hospital, Cheongju, Republic of Korea.ORCID 0000-0003-0007-1960
So Hyeon BakDepartment of Radiology, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.ORCID 0000-0003-1039-7016
Jin Young KimDepartment of Radiology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.ORCID 0000-0001-6714-8358
Jin Hwan KimDepartment of Radiology, Chungnam National University Hospital, College of Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-1632-2421
Ki Beom KimDepartment of Radiology, Daegu Fatima Hospital, Daegu, Republic of Korea.ORCID 0000-0003-4508-6058
Jung Im JungDepartment of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0001-8264-9388
Jae-Kwang LimDepartment of Radiology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0002-1299-9996
Jong Eun LeeDepartment of Radiology, Chonnam National University Hospital, Gwangju, Republic of Korea.ORCID 0000-0002-8754-6801
Myung Jin ChungDepartment of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-6271-3343
Young Kyung LeeDepartment of Radiology, Seoul Medical Center, Seoul, Republic of Korea.ORCID 0000-0001-6953-0972
Young Seon KimDepartment of Radiology, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, Republic of Korea.ORCID 0000-0002-9168-8204
Sang Min LeeDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-2173-2193
Woocheol KwonDepartment of Radiology, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea.ORCID 0000-0003-0397-4364
Chang Min ParkCollege of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0003-1884-3738
Yun-Hyeon KimDepartment of Radiology, Chonnam National University Hospital, Gwangju, Republic of Korea.ORCID 0000-0002-0047-0729
Yeon Joo JeongDepartment of Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, Republic of Korea.ORCID 0000-0002-1741-9604
Kwang Nam JinCollege of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0001-5494-9113
Jin Mo GooCollege of Medicine, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0003-1791-7942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn artificial intelligence (AI) model using chest radiography (CXR) may provide good performance in making prognoses for COVID-19.

objectiveWe aimed to develop and validate a prediction model using CXR based on an AI model and clinical variables to predict clinical outcomes in patients with COVID-19.

methodsThis retrospective longitudinal study included patients hospitalized for COVID-19 at multiple COVID-19 medical centers between February 2020 and October 2020. Patients at Boramae Medical Center were randomly classified into training, validation, and internal testing sets (at a ratio of 8:1:1, respectively). An AI model using initial CXR images as input, a logistic regression model using clinical information, and a combined model using the output of the AI model (as CXR score) and clinical information were developed and trained to predict hospital length of stay (LOS) ≤2 weeks, need for oxygen supplementation, and acute respiratory distress syndrome (ARDS). The models were externally validated in the Korean Imaging Cohort of COVID-19 data set for discrimination and calibration.

resultsThe AI model using CXR and the logistic regression model using clinical variables were suboptimal to predict hospital LOS ≤2 weeks or the need for oxygen supplementation but performed acceptably in the prediction of ARDS (AI model area under the curve [AUC] 0.782, 95% CI 0.720-0.845; logistic regression model AUC 0.878, 95% CI 0.838-0.919). The combined model performed better in predicting the need for oxygen supplementation (AUC 0.704, 95% CI 0.646-0.762) and ARDS (AUC 0.890, 95% CI 0.853-0.928) compared to the CXR score alone. Both the AI and combined models showed good calibration for predicting ARDS (P=.079 and P=.859).

conclusionsThe combined prediction model, comprising the CXR score and clinical information, was externally validated as having acceptable performance in predicting severe illness and excellent performance in predicting ARDS in patients with COVID-19.

Indexed as

COVID-19Deep LearningRespiratory Distress SyndromeArtificial IntelligenceHumansLongitudinal StudiesOxygenPrognosisRadiographyRetrospective StudiesOxygenAI modelartificial intelligenceclinical outcomeCOVID-19deep learningmachine learningmedical imagingprediction modelprognosisradiography, thoracic

Identifiers

PMID36795468
PMCPMC9937110

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.