Evidence map›Paper›PMID 36795298›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2023

Internal carotid artery dissection in a patient with hemophilia A: a case report and literature review.

Salvatore Iacono, Roberta Baschi, Lucia Di Giorgi, Cesare Gagliardo, Alessandro Pezzini, Roberto Monastero

Abstract readReviewCase Reports
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Salvatore IaconoSection of Neurology, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BiND), University of Palermo, 90121, Palermo, Italy.
Roberta BaschiSection of Neurology, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BiND), University of Palermo, 90121, Palermo, Italy.
Lucia Di GiorgiSection of Neurology, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BiND), University of Palermo, 90121, Palermo, Italy.
Cesare GagliardoSection of Radiology, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BiND), University of Palermo, 90121, Palermo, Italy.
Alessandro PezziniDepartment of Clinical and Experimental Sciences, University of Brescia, 25123, Brescia, Italy.
Roberto MonasteroSection of Neurology, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BiND), University of Palermo, 90121, Palermo, Italy. roberto.monastero@unipa.it.ORCID http://orcid.org/0000-0002-2829-523X
University of Palermo · ITUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous cervical artery dissection (sCeAD) is the most common cause of ischemic stroke at a young age, but its pathogenetic mechanism and risk factors are not fully elucidated. It is reasonable to think that bleeding propensity, vascular risk factors such as hypertension and head or neck trauma, and constitutional weakness of the arterial wall together play a role in the pathogenesis of sCeAD. Hemophilia A is known to be an X-linked condition that leads to spontaneous bleeding in various tissues and organs. To date, a few cases of acute arterial dissection in patients with hemophilia have been reported, but the relationship between these two diseases has not been studied so far. In addition, there are no guidelines indicating the best antithrombotic treatment option in these patients. We report the case of a man with hemophilia A who developed sCeAD and transient oculo-pyramidal syndrome and was treated with acetylsalicylic acid. We also review previous published cases of arterial dissection in patients with hemophilia, discussing the potential pathogenetic mechanism underlying this rare association and potential antithrombotic therapeutic options.

Indexed as

Carotid Artery, Internal, DissectionHemophilia AHypertensionStrokeVertebral Artery DissectionCarotid Artery, InternalFibrinolytic AgentsHumansMaleRisk FactorsFibrinolytic AgentsAntithrombotic drugsCervical artery dissectionHemophiliaNeck trauma

Identifiers

PMID36795298
OpenAlexW4321003593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.