ArticleBioinformatics (Oxford, England)2023
VirBot: an RNA viral contig detector for metagenomic data.
Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- RdRpCATCH: a unified resource for RNA virus discovery using viral RNA-dependent RNA polymerase profile Hidden Markov models.NAR genomics and bioinformatics · 2026Article
- Identification and complete genome sequence of a novel secovirus infecting Broussonetia kaempferi in China.Archives of virology · 2026Article
- TITAN-RNA: A hybrid-capture sequencing panel detects known and unknownbioRxiv : the preprint server for biology · 2025Article
- Diverse ssRNA viruses associated withmSphere · 2025Article
- Virome diversity and potential sharing of wild mammals in a biodiversity hotspot, Yunnan, China.Virology journal · 2025Article
- Article
- Metavirome Identification and Pathogenicity Evaluation of Tibet Orbivirus in Pigs.Transboundary and emerging diseases · 2025Article
- VirID: Beyond Virus Discovery-An Integrated Platform for Comprehensive RNA Virus Characterization.Molecular biology and evolution · 2024Article
- Reproducible chemostat cultures to minimize eukaryotic viruses from fecal transplant material.iScience · 2024Article
- SegVir: Reconstruction of Complete Segmented RNA Viral Genomes from Metatranscriptomes.Molecular biology and evolution · 2024Article
- Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments.Microbiome · 2024Article
- Transfer of modified gut viromes improves symptoms associated with metabolic syndrome in obese male mice.Nature communications · 2024Article
- Utilizing profile hidden Markov model databases for discovering viruses from metagenomic data: a comprehensive review.Briefings in bioinformatics · 2024Review
- A widespread picornavirus affects the hemocytes of the noble pen shell (Frontiers in veterinary science · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
summaryWithout relying on cultivation, metagenomic sequencing greatly accelerated the novel RNA virus detection. However, it is not trivial to accurately identify RNA viral contigs from a mixture of species. The low content of RNA viruses in metagenomic data requires a highly specific detector, while new RNA viruses can exhibit high genetic diversity, posing a challenge for alignment-based tools. In this work, we developed VirBot, a simple yet effective RNA virus identification tool based on the protein families and the corresponding adaptive score cutoffs. We benchmarked it with seven popular tools for virus identification on both simulated and real sequencing data. VirBot shows its high specificity in metagenomic datasets and superior sensitivity in detecting novel RNA viruses. AVAILABILITY AND IMPLEMENTATION: https://github.com/GreyGuoweiChen/RNA_virus_detector. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.