Evidence map›Paper›PMID 36794908›Full record

ArticleeLife2023

SUMOylation of Na

Oron Kotler, Yana Khrapunsky, Arik Shvartsman, Hui Dai, Leigh D Plant, Steven A N Goldstein, Ilya Fleidervish

Open access · goldFull text read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 18 citations in OpenAlex.

  1. mTORC2-NaChannels (Austin, Tex.) · 2026
    Article
  2. Review
  3. Article
  4. Spatiotemporal Dynamics of Lateral NaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Cytoskeletal scaffolding of NaCurrent opinion in cell biology · 2025
    Review
  6. Spatio-temporal dynamics of lateral NabioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. DecipheringArXiv · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. SUMOylation of NaeLife · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Oron KotlerDepartment of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.ORCID 0000-0003-1698-545X
Yana KhrapunskyDepartment of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Arik ShvartsmanDepartment of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Hui DaiDepartments of Pediatrics and Physiology and Biophysics, University of California, Irvine, Irvine, United States.ORCID 0000-0002-0440-7815
Leigh D PlantDepartment of Pharmaceutical Sciences, Northeastern University, Boston, United States.ORCID 0000-0002-1622-1655
Steven A N GoldsteinDepartments of Pediatrics and Physiology and Biophysics, University of California, Irvine, Irvine, United States.ORCID 0000-0001-5207-5061
Ilya FleidervishDepartment of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.ORCID 0000-0002-5501-726X
Ben-Gurion University of the Negev · ILUniversity of California, Irvine · USNortheastern University · US

Funding

SUMO-regulation of ion channels via PIP2R01HL144615 · NHLBI · NORTHEASTERN UNIVERSITY · PI PLANT, LEIGH DANIEL · 2019 to 2022
$1.6M
NHLBI NIH HHS R01 HL144615NIH HHS R01HL10549
6 · The paper itself

Abstract

Voltage-gated sodium channels located in axon initial segments (AIS) trigger action potentials (AP) and play pivotal roles in the excitability of cortical pyramidal neurons. The differential electrophysiological properties and distributions of Na

Indexed as

Axon Initial SegmentSumoylationAction PotentialsAnimalsMiceNeuronsPyramidal Cellsaction potentialaxon initial segmentbackpropagationmouseneurosciencepersistent sodium currentpyramidal neuronSUMO

Identifiers

PMID36794908
PMCPMC10014073
OpenAlexW4321003723

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read51
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.