Evidence map›Paper›PMID 36794756›Full record

ArticleAmerican journal of physiology. Renal physiology2023

Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation.

Mary Claire Doss, Sean Mullen, Ronald Roye, Juling Zhou, Phillip Chumley, Elias Mrug, Darren P Wallace, Feng Qian, Peter C Harris, Bradley K Yoder and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Mary Claire DossDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Sean MullenDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Ronald RoyeDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Juling ZhouDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Phillip ChumleyDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Elias MrugMath-Science Department, Alabama School of Fine Arts, Birmingham, Alabama, United States.
Darren P WallaceThe Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0003-4616-7669
Feng QianDivision of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0001-9595-9772
Peter C HarrisDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States.
Bradley K YoderDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Harrison KimDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0002-9126-1964
Michal MrugDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0001-8981-1843
University of Alabama at Birmingham · USAlabama School of Fine Arts · USMayo Clinic · USUniversity of Kansas Medical Center · USUniversity of Maryland, Baltimore · US

Funding

UAB Pilot Center for Precision Animal Modeling (C-PAM) - Resource and Service SectionU54OD030167 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Bradley K. Yoder · 2020 to 2026
$15.3M
UAB Childhood Cystic Kidney Disease Core Center (UAB-CCKDCC) - Therapeutic Development and Screening ResourceU54DK126087 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LISA MARIE GUAY-WOODFORD · 2020 to 2026
$6.7M
Polycystin Function Resource Development CoreU54DK126126 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Alan S Yu · 2020 to 2026
$5.8M
Intra-renal T-cell heterogeneity in ADPKD patientsI01BX004232 · VA · BIRMINGHAM VA MEDICAL CENTER · PI MRUG, MICHAL · 2020 to 2023
–
BLRD VA I01 BX004232NIDDK NIH HHS U54 DK126087NIDDK NIH HHS U54 DK126126NIH HHS U54 OD030167
6 · The paper itself

Abstract

Measurement of total kidney volume (TKV) using magnetic resonance imaging (MRI) is a valuable approach for monitoring disease progression in autosomal dominant polycystic kidney disease (PKD) and is becoming more common in preclinical studies using animal models. Manual contouring of kidney MRI areas [i.e., manual method (MM)] is a conventional, but time-consuming, way to determine TKV. We developed a template-based semiautomatic image segmentation method (SAM) and validated it in three commonly used PKD models:

Indexed as

Polycystic Kidney, Autosomal DominantPolycystic Kidney, Autosomal RecessiveAnimalsKidneyMicePolycystic Kidney DiseasesRatsReceptors, Cell SurfaceRodentiaPkhd1 protein, mouseReceptors, Cell Surfaceanimal imagingautosomal dominant polycystic kidney diseaseautosomal recessive polycystic kidney diseaseimage analysis toolsmagnetic resonance imaging

Identifiers

PMID36794756
PMCPMC10069971
OpenAlexW4321003917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.