Evidence map›Paper›PMID 36794623›Full record

ArticleEMBO reports2023

Reverse electron transfer is activated during aging and contributes to aging and age-related disease.

Suman Rimal, Ishaq Tantray, Yu Li, Tejinder Pal Khaket, Yanping Li, Sunil Bhurtel, Wen Li, Cici Zeng, Bingwei Lu

Open access · greenAbstract read
In one paragraph

Article in EMBO reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Suman RimalDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Ishaq TantrayDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Yu LiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Tejinder Pal KhaketDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Yanping LiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Sunil BhurtelDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Wen LiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Cici ZengPomfret School, Pomfret, CT, USA.
Bingwei LuDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-5807-7014
Stanford University · USPomfret School · US

Funding

Molecular Genetic Analysis of TORC1 and TORC2 Signaling in Neuronal MaintenanceR01NS084412 · NINDS · STANFORD UNIVERSITY · PI Bingwei Lu · 2014 to 2026
$4.9M
Mitochondrial inner membrane architecture in skeletal muscle pathophysiologyR01AR074875 · NIAMS · STANFORD UNIVERSITY · PI LU, BINGWEI · 2019 to 2023
$2.0M
NIAMS NIH HHS R01 AR074875NINDS NIH HHS R01 NS084412
6 · The paper itself

Abstract

Mechanisms underlying the depletion of NAD

Indexed as

Alzheimer DiseaseInduced Pluripotent Stem CellsAgingAnimalsDrosophilaElectronsHumansMiceNADReactive Oxygen SpeciesNADReactive Oxygen SpeciesAlzheimer's diseaselifespanmitochondrial complex INAD+/NADH ratioreverse electron transport

Identifiers

PMID36794623
PMCPMC10074108
OpenAlexW4321004238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.