Evidence map›Paper›PMID 36794189›Full record

ArticleChemical science2023

Coupling of α-bromoamides and unactivated alkenes to form γ-lactams through EDA and photocatalysis.

Sean M Treacy, Daniel R Vaz, Syed Noman, Cédric Tard, Tomislav Rovis

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  4. Visible-light-inducedRSC advances · 2024
    Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sean M TreacyDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.
Daniel R VazDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.ORCID https://orcid.org/0000-0003-4995-5724
Syed NomanLaboratoire de Chimie Moléculaire (LCM), CNRS, École Polytechnique, Institut Polytechnique de Paris 91120 Palaiseau France.
Cédric TardLaboratoire de Chimie Moléculaire (LCM), CNRS, École Polytechnique, Institut Polytechnique de Paris 91120 Palaiseau France.ORCID https://orcid.org/0000-0002-1515-1915
Tomislav RovisDepartment of Chemistry, Columbia University New York NY 10027 USA tr2504@columbia.edu.ORCID https://orcid.org/0000-0001-6287-8669
Columbia University · USCentre National de la Recherche Scientifique · FR

Funding

Selective Functionalization of Aliphatic Amines - Supplement to Support Mariah RamosR01GM125206 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ROVIS, TOMISLAV · 2017 to 2024
$2.6M
NIGMS NIH HHS R01 GM125206
6 · The paper itself

Abstract

γ-Lactams are prevalent in small-molecule pharmaceuticals and provide useful precursors to highly substituted pyrrolidines. Despite numerous methods for the synthesis of this valuable motif, previous redox approaches to γ-lactam synthesis from α-haloamides and olefins require additional electron withdrawing functionality as well as

Identifiers

PMID36794189
PMCPMC9906710
OpenAlexW4317613527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.