ArticleJournal of thoracic disease2023
Risk factors and clinical outcomes associated with acquired hypofibrinogenemia in patients administered hemocoagulase batroxobin for hemoptysis.
Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Evaluation of the ability of hemostatic agents to prevent hemoptysis during ultrasound-guided lung biopsy.Quantitative imaging in medicine and surgery · 2026Article
- Initial experiences of the transthoracic esophagectomy for esophageal cancer via intercostal approach with the single-port robotic surgical system.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- A retrospective study of risk factors contributing to hemocoagulase-induced hypofibrinogenemia in hemoptysis patients.Journal of thoracic disease · 2025Article
- Risk factors for hemocoagulase-associated hypofibrinogenemia in patients with gastrointestinal bleeding.World journal of gastrointestinal surgery · 2024Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hemocoagulase batroxobin is used to prevent hemostasis or bleeding in surgical and trauma patients; however, the role of batroxobin in patients with hemoptysis is not well understood. We evaluated the risk factors and prognosis of acquired hypofibrinogenemia in hemoptysis patients treated systemically with batroxobin. Methods: We retrospectively reviewed the medical charts of hospitalized patients who were administered batroxobin for hemoptysis. Acquired hypofibrinogenemia was defined as a plasma fibrinogen level >150 mg/dL at baseline, decreasing to <150 mg/dL after batroxobin administration. Results: Overall, 183 patients were enrolled, of whom 75 had acquired hypofibrinogenemia after the administration of batroxobin. There was no statistical difference in the median age of the patients in the non-hypofibrinogenemia and hypofibrinogenemia groups (72.0 Conclusions: The plasma fibrinogen levels in patients who were administered batroxobin for hemoptysis should be monitored, and batroxobin should be discontinued if hypofibrinogenemia occurs.
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