ArticleNeurobiology of language (Cambridge, Mass.)2020
Gene Expression Correlates of the Cortical Network Underlying Sentence Processing.
Article in Neurobiology of language (Cambridge, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Variations of global brain asymmetry are associated with aging and related diseases.Science advances · 2026Article
- Multiscale neural features of tonal bilingualism: linking regional differences in brain network degree centrality to neurotransmitter-gene signatures in Bai-Mandarin bilinguals.Scientific reports · 2026Article
- NEBULA101: an open dataset for the study of language aptitude in behaviour, brain structure and function.Scientific data · 2025Article
- The neocortical infrastructure for language involves region-specific patterns of laminar gene expression.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Processing Language Partly Shares Neural Genetic Basis with Processing Tools and Body Parts.eNeuro · 2024Article
- Review
- Uncovering the genetic profiles underlying the intrinsic organization of the human cerebellum.Molecular psychiatry · 2022Article
- The Musical Abilities, Pleiotropy, Language, and Environment (MAPLE) Framework for Understanding Musicality-Language Links Across the Lifespan.Neurobiology of language (Cambridge, Mass.) · 2022Review
- Deep Learning-based Classification of Resting-state fMRI Independent-component Analysis.Neuroinformatics · 2021Article
- Large-Scale Phenomic and Genomic Analysis of Brain Asymmetrical Skew.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Expression of CRY2 Gene in the Brain Is Related to Human Navigation.Frontiers in radiology · 2021Article
- The Domain-General Multiple Demand (MD) Network Does Not Support Core Aspects of Language Comprehension: A Large-Scale fMRI Investigation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Article
- A 3.5-minute-long reading-based fMRI localizer for the language network.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A pivotal question in modern neuroscience is which genes regulate brain circuits that underlie cognitive functions. However, the field is still in its infancy. Here we report an integrated investigation of the high-level language network (i.e., sentence-processing network) in the human cerebral cortex, combining regional gene expression profiles, task fMRI, large-scale neuroimaging meta-analysis, and resting-state functional network approaches. We revealed reliable gene expression-functional network correlations using three different network definition strategies, and identified a consensus set of genes related to connectivity within the sentence-processing network. The genes involved showed enrichment for neural development and actin-related functions, as well as association signals with autism, which can involve disrupted language functioning. Our findings help elucidate the molecular basis of the brain's infrastructure for language. The integrative approach described here will be useful for studying other complex cognitive traits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.