Evidence map›Paper›PMID 36794003›Full record

Trial reportFrontiers in cellular and infection microbiology2023

High-fiber diet ameliorates gut microbiota, serum metabolism and emotional mood in type 2 diabetes patients.

Lihua Chen, Bo Liu, Lixia Ren, Hao Du, Chunhua Fei, Chang Qian, Bin Li, Ruixia Zhang, Haixia Liu, Zongjie Li and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07255170 (DEVELOPMENT OF "GLYCEMIC CONTROL BAR WITH BEANS AND TOMATO FOR DIABETIC EATING"), which is not on this map. Cited by 111 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 3 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07255170 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Development of "glycemic control bar with beans and tomato for diabetic eating" (glycobite) snack bar formulations as a healthy snack for diabetes mellitus patients

TypeinterventionalSponsorUniversity Ngudi WaluyoRan2025 to 2025Enrolled100ConditionsDiabetes MellitusArmsThe GlycoBite snack bar formula created is to combine tomatoes and red beans in a ratio of 60% and 40% respectively. Participants consuming 40 grams of "GlycoBite" snack bars daily
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 3 syntheses or guidelines pooled it, 134 citations in OpenAlex.

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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Lihua ChenSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, China.
Bo LiuSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, China.
Lixia RenSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, China.
Hao DuDepartment of Gastroenterology, Mental Health Center of Fengxian District, Shanghai, China.
Chunhua FeiDepartment of Gastroenterology, Mental Health Center of Fengxian District, Shanghai, China.
Chang QianDepartment of Gastroenterology, Mental Health Center of Fengxian District, Shanghai, China.
Bin LiShanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ruixia ZhangShanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haixia LiuSafety & Quality Management Department, Sino-science Yikang (Beijing) Biotech Co., Ltd, Beijing, China.
Zongjie LiSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, China.
Zhiyong MaShanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China.
Shanghai Institute of Technology · CNXian Mental Health Center · CNShanghai Jiao Tong University · CNShanghai Veterinary Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated that patients with type 2 diabetes mellitus (T2DM) often had the problems of fecal microbiota dysbiosis, and were usually accompanied with psychiatric comorbidities (such as depression and anxiety). Here, we conducted a randomized clinical study to analyze the changes in gut microbiota, serum metabolism and emotional mood of patients with T2DM after consumption of a high-fiber diet. The glucose homeostasis of participants with T2DM was improved by the high-fiber diet, and the serum metabolome, systemic inflammation and psychiatric comorbidities were also altered. The increased abundances of

Indexed as

Diabetes Mellitus, Type 2Gastrointestinal MicrobiomeMicrobiotaDietHumansInflammationanxietydepressiondietary fibergut microbiotaserum metabolometype 2 diabetes mellitus

Identifiers

PMID36794003
PMCPMC9922700
OpenAlexW4318590499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.