Evidence map›Paper›PMID 36793934›Full record

ArticleEuropean heart journal. Case reports2023

Caplacizumab for treating subacute intra-stent thrombus occurring despite efficacious double anti-platelet treatment and anticoagulation: a case report.

Gregoire Stalder, Antoine Chatte, Noemy De Rossi, Patrick Yerly, Lorenzo Alberio, Eric Eeckhout

Open access · goldAbstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Identification of High Platelet Reactivity Despite ADP P2YTH open : companion journal to thrombosis and haemostasis · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gregoire StalderService and Central Laboratory of Hematology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), rue du Bugnon 46, CH-1011 Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-0536-5418
Antoine ChatteDepartment of Cardiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), rue du Bugnon 46, CH-1011 Lausanne, Switzerland.
Noemy De RossiService and Central Laboratory of Hematology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), rue du Bugnon 46, CH-1011 Lausanne, Switzerland.
Patrick YerlyDepartment of Cardiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), rue du Bugnon 46, CH-1011 Lausanne, Switzerland.
Lorenzo AlberioService and Central Laboratory of Hematology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), rue du Bugnon 46, CH-1011 Lausanne, Switzerland.ORCID https://orcid.org/0000-0001-9686-9920
Eric EeckhoutDepartment of Cardiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), rue du Bugnon 46, CH-1011 Lausanne, Switzerland.
University Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute and subacute stent thromboses are a rare complication associated with high mortality and morbidity occurring in ∼1.5% of patients treated with primary percutaneous intervention for ST-elevation myocardial infarction (STEMI). Recent publications describe a potential role of the von Willebrand factor (VWF) in thrombus formation at sites of critical coronary stenosis in STEMI. Case summary: We describe a 58-year-old woman with STEMI at initial presentation, who suffered subacute stent thrombosis despite good stent expansion, efficacious dual antiplatelet therapy, and therapeutic anticoagulation. Because of very high VWF values, we administered Discussion: Considering a modern view of intracoronary thrombus pathophysiology, we describe an innovative treatment approach, which eventually ended in a favourable outcome.

Indexed as

CaplacizumabCase ReportN-acetylcysteineSTEMISubacute stent thrombosisvon Willebrand factor

Identifiers

PMID36793934
PMCPMC9924497
OpenAlexW4317207084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.