Evidence map›Paper›PMID 36793921›Full record

ArticleFrontiers in pharmacology2022

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid.

Ke Li, Xiu-Hua Yu, Anish R Maskey, Ibrahim Musa, Zhen-Zheng Wang, Victor Garcia, Austin Guo, Nan Yang, Kamal Srivastava, David Dunkin and 6 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Advancements and emerging trends in photodynamic therapy: innovations in cancer treatment and beyond.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  6. The Potential ofInternational journal of molecular sciences · 2025
    Article
  7. Review
  8. Effects ofPreventive nutrition and food science · 2025
    Article
  9. False Positive Cushing's Syndrome in a 16-Year-Old Male.International journal of endocrinology and metabolism · 2025
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ke LiGuangdong Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, China.
Xiu-Hua YuDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
Anish R MaskeyDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
Ibrahim MusaDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
Zhen-Zheng WangDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
Victor GarciaDepartment of Pharmacology, New York Medical College, Valhalla, NY, United States.
Austin GuoDepartment of Pharmacology, New York Medical College, Valhalla, NY, United States.
Nan YangDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
Kamal SrivastavaDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
David DunkinDepartment of Pediatrics, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Jun-Xiong LiGuangdong Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, China.
Longgang GuoGuangzhou ImVin Pharmaceutical Co., Ltd., Guangzhou, China.
Yung-Chi ChengDepartment of Pharmacology, School of Medicine, Yale University, New Haven, China.
Haoliang YuanJiangsu Key Laboratory of Drug Discovery for Metabolic Disease and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Raj TiwariDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.
Xiu-Min LiDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-inflammationCYP3A4drug-drug interaction (DDI)epimediumkaempferol

Identifiers

PMID36793921
PMCPMC9922998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.