Evidence map›Paper›PMID 36793713›Full record

ArticleFrontiers in immunology2023

Retinal structural and microvascular changes in myelin oligodendrocyte glycoprotein antibody disease and neuromyelitis optica spectrum disorder: An OCT/OCTA study.

Yanlin Lang, William Robert Kwapong, Lingyao Kong, Ziyan Shi, Xiaofei Wang, Qin Du, Bo Wu, Hongyu Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yanlin LangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
William Robert KwapongDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Lingyao KongDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Ziyan ShiDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Xiaofei WangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Qin DuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Bo WuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Hongyu ZhouDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the optical coherence tomography (OCT)/OCT angiography (OCTA) measures in patients with neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD). Methods: Twenty-one MOG, 21 NMOSD, and 22 controls were enrolled in our study. The retinal structure [retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL)] was imaged and assessed with the OCT; OCTA was used to image the macula microvasculature [superficial vascular plexus (SVP), intermediate capillary plexus (ICP), and deep capillary plexus (DCP)]. Clinical information such as disease duration, visual acuity, and frequency of optic neuritis and disability was recorded for all patients. Results: Compared with NMOSD patients, MOGAD patients showed significantly reduced SVP density ( Conclusions: Distinct structural and microvascular changes were identified in MOGAD patients compared with NMOSD patients suggesting that the pathological mechanisms are different in NMOSD and MOGAD. Retinal imaging

Indexed as

Macula LuteaNeuromyelitis OpticaOptic NeuritisHumansMyelin-Oligodendrocyte GlycoproteinRetinaMyelin-Oligodendrocyte Glycoproteinmacula microvasculaturemyelin oligodendrocyte glycoprotein antibody diseaseneuromyelitis optica spectrum disorderoptical coherence tomographyoptical coherence tomography angiography

Identifiers

PMID36793713
PMCPMC9923098
OpenAlexW4318473045

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.