Evidence map›Paper›PMID 36793603›Full record

ArticleFrontiers in oncology2023

Relapsed/refractory diffuse large B cell lymphoma with cardiac involvement: A case report and literature review.

Yuanyuan Yang, Zixuan Li, Yuntao Li, Yue Zhao, Mingxia Shi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Cardiac Involvement in Thoracic Lymphoma.Clinical case reports · 2025
    Article
  2. Article
  3. The clinical landscape of CAR NK cells.Experimental hematology & oncology · 2025
    Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuanyuan YangDepartment of Hematology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zixuan LiDepartment of Hematology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yuntao LiDepartment of Hematology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yue ZhaoDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
Mingxia ShiDepartment of Hematology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
First Affiliated Hospital of Kunming Medical University · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hematological malignancies of the heart (CHMs) are extremely rare, and include leukemia, lymphoma infiltration, and multiple myeloma with extramedullary manifestations. Cardiac lymphoma can be divided into primary cardiac lymphoma (PCL) and secondary cardiac lymphoma (SCL). Compared to PCL, SCL is relatively more common. Histologically, the most frequent SCL is diffuse large B-cell lymphoma (DLBCL). The prognosis of lymphoma in patients with cardiac involvement is extremely poor. CAR T-cell immunotherapy has been recently become a highly effective treatment for relapsed or refractory diffuse large B-cell lymphoma. To date, there are no guidelines that provide a clear consensus on the management of patients with secondary heart or pericardial involvement. We report a case of relapsed/refractory DLBCL that secondarily affected the heart. Case presentation: A male patient was diagnosed with double-expressor DLBCL based on biopsies of mediastinal and peripancreatic masses and fluorescence Conclusion: The response of our patient emphasizes the importance of early diagnosis and timely treatment to improve the prognosis of SCL and serves as an important reference for SCL treatment strategies.

Indexed as

B-cell lymphomacardiac hematological malignancyCAR T-cell immunotherapycase reportsecondary cardiac lymphoma

Identifiers

PMID36793603
PMCPMC9923120
OpenAlexW4318473806

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.