Evidence map›Paper›PMID 36793541›Full record

ArticleFrontiers in neuroscience2023

Regional high iron deposition on quantitative susceptibility mapping correlates with cognitive decline in type 2 diabetes mellitus.

Rui Hu, Bingbing Gao, Shiyun Tian, Yangyingqiu Liu, Yuhan Jiang, Wanyao Li, Yuan Li, Qingwei Song, Weiwei Wang, Yanwei Miao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Review
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  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rui HuDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Bingbing GaoDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Shiyun TianDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yangyingqiu LiuDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yuhan JiangDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Wanyao LiDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yuan LiDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Qingwei SongDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Weiwei WangDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yanwei MiaoDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To quantitatively evaluate the iron deposition and volume changes in deep gray nuclei according to threshold-method of quantitative susceptibility mapping (QSM) acquired by strategically acquired gradient echo (STAGE) sequence, and to analyze the correlation between the magnetic susceptibility values (MSV) and cognitive scores in type 2 diabetes mellitus (T2DM) patients. Methods: Twenty-nine patients with T2DM and 24 healthy controls (HC) matched by age and gender were recruited in this prospective study. QSM images were used to evaluate whole-structural volumes (V Results: Compared with HC group, the MSV Conclusion: In T2DM patients, excessive and heterogeneous iron deposition as well as volume loss occurs in deep gray nuclei. The MSV in high iron regions can better evaluate the distribution of iron, which is related to the decline of cognitive function.

Indexed as

brain iron depositiondeep gray nucleiheterogeneitymagnetic sensitivity valuequantitative susceptibility mappingtype 2 diabetes mellitusvolume

Identifiers

PMID36793541
PMCPMC9922715
OpenAlexW4318457156

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.