ArticleFrontiers in surgery2022
Clinical features and prognostic factors analysis of intravenous leiomyomatosis.
Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Molecular and Genetic Landscape of Intravenous Leiomyomatosis: A Narrative Review.Cancer innovation · 2026Review
- Transesophageal Echocardiography-Guided Anesthetic Management of Intravenous Leiomyomatosis With Right Atrial Extension: A Case Report.A&A practice · 2026Article
- Case report of the management of intravascular leiomyomatosis including uterine surgery, vascular surgery, hormonal management, and in vitro fertilization.Journal of vascular surgery cases and innovative techniques · 2026Article
- Single-stage laparotomy for intracardiac leiomyomatosis without open-heart surgery: a case report.BMC cardiovascular disorders · 2026Article
- Intravenous leiomyomatosis manifesting as a cardiac mass: a case report.Frontiers in cardiovascular medicine · 2026Article
- MRI Features of Intravenous Leiomyomatosis.Journal of the Belgian Society of Radiology · 2026Article
- Perioperative anesthetic management in patients undergoing resection of giant abdominal masses: a retrospective analysis of 21 cases.Frontiers in oncology · 2026Article
- Multidisciplinary management of intravenous leiomyomatosis extending to the inferior vena cava and heart: a case series.BMC cardiovascular disorders · 2025Article
- Intravenous Leiomyomatosis in a 20-Year-Old Nulliparous Woman: Atypical Presentation and Radiological Investigation.Cureus · 2025Article
- Uterine Intravenous Leiomyomatosis with Internal Iliac Artery Involvement.International journal of women's health · 2025Article
- Pathological characteristics and clinical prognostic analysis of intravenous leiomyomatosis: a retrospective study of 43 cases.Frontiers in medicine · 2025Article
- Three Cases of Intracardiac Leiomyomatosis with Very Long-term Follow-up.Vascular specialist international · 2024Article
- Multimodality imaging applications in the diagnosis of and surgical treatment strategy for intravenous leiomyomatosis: a case description and literature analysis.Quantitative imaging in medicine and surgery · 2024Article
- Analysis of risk factors for post-operative recurrence or progression of intravenous leiomyomatosis.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Uterine intravascular leiomyomatosis involves the heart: a case report and literature review.Translational cancer research · 2023Article
- "Evolution" of intravascular leiomyomatosis.BMC women's health · 2023Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The treatment and prognostic factors of intravenous leiomyomatosis (IVL) remain lacking systematic evidence. Methods: A retrospective study was conducted on IVL patients from the Qilu Hospital of Shandong University, and IVL cases were published in PubMed, MEDLINE, Embase and Cochrane Library databases. Descriptive statistics were used for the basic characteristics of patients. The Cox proportional hazards regression analysis was used to assess the high-risk factors related to the progression-free survival (PFS). The comparison of survival curves was performed by Kaplan-Meier analysis. Results: A total of 361 IVL patients were included in this study, 38 patients from Qilu Hospital of Shandong University, and 323 patients from the published literature. Age ≤45 years was observed in 173 (47.9%) patients. According to the clinical staging criteria, stage I/II was observed in 125 (34.6%) patients, and stage III/IV was observed in 221 (61.2%) patients. Dyspnea, orthopnea, and cough were observed in 108 (29.9%) patients. Completed tumor resection was observed in 216 (59.8%) patients, and uncompleted tumor resection was observed in 58 (16.1%) patients. Median follow-up period was 12 months (range 0-194 months), and 68 (18.8%) recurrences or deaths were identified. The adjusted multivariable Cox proportional hazard analysis showed age ≤45 years (vs. >45) (hazard ratio [HR] = 2.09, 95% confidence interval [CI] 1.15-3.80, Conclusion: Patients with IVL have a high probability of recurrence after surgery and a poor prognosis. Patients younger than 45 years and with uncompleted tumor resection are at higher risk of postoperative recurrence or death.
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