ArticleJournal of the Endocrine Society2023
Visceral Adipose Tissue is Negatively Associated With Bone Mineral Density in NHANES 2011-2018.
Article in Journal of the Endocrine Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A systematic review of the association between insulin resistance surrogate indices and bone mineral density.Frontiers in endocrinology · 2024Pooled it
- Differential associations of subcutaneous and visceral fat with bone turnover markers: A study on bariatric surgery patients with severe obesity and individuals without obesity.International journal of obesity (2005) · 2025Trial
- Why Do We Lose Bone During Weight Loss: Can It Be Prevented?Current osteoporosis reports · 2026Review
- Deciphering inter-organ communication: The multi-organ-bone axis in osteoporosis and emerging therapeutic strategies.Journal of orthopaedic translation · 2026Review
- HDL-C and systemic inflammatory response index mediate the association between visceral adipose tissue and risk of cardiovascular disease among young and middle-aged adults with prediabetes or diabetes: a national cohort study.Journal of translational medicine · 2025Article
- Association of serum urea-to-creatinine and creatinine-to-cystatin C ratios with bone mineral density and osteoporosis: a cross-sectional study.Scientific reports · 2025Article
- Abdominal and hip fat percentages are associated with fragility fractures: evidence from a large cross-sectional study.Scientific reports · 2025Article
- Enhancing Bone Health with Conjugated Linoleic Acid: Mechanisms, Challenges, and Innovative Strategies.Nutrients · 2025Review
- Associations between abdominal fat, psoas muscle fat, and lumbar spine bone density: insights from quantitative CT imaging.BMC musculoskeletal disorders · 2025Article
- Article
- Commentary: Negative association between Body Roundness Index and bone mineral density: insights from NHANES.Frontiers in nutrition · 2025Article
- Observational
- Bone metabolism in diabetes: a clinician's guide to understanding the bone-glucose interplay.Diabetologia · 2024Review
- Maternal diabetes and fracture risk in offspring: a population-based analysis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Bone mineral density in young adults 5 to 11 years after adolescent metabolic and bariatric surgery for severe obesity compared to peers.International journal of obesity (2005) · 2024Article
- The different association between fat mass distribution and intake of three major nutrients in pre- and postmenopausal women.PloS one · 2024Article
- Lipid accumulation product, poverty income ratio, and bone mineral density in U.S. adults: a mediation analysis based on NHANES (2009-2020).Frontiers in nutrition · 2024Article
- Diet-Stimulated Marrow Adiposity Fails to Worsen Early, Age-Related Bone Loss.Obesity facts · 2024Article
- Visceral Adipose Tissue is Negatively Associated With Bone Mineral Density in NHANES 2011-2018.Journal of the Endocrine Society · 2023Article
- The complex pathophysiology of bone fragility in obesity and type 2 diabetes mellitus: therapeutic targets to promote osteogenesis.Frontiers in endocrinology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: The relationship of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with bone mineral density (BMD) is not well established. Objective: To examine the associations of VAT and SAT with total body BMD in a large, nationally representative population with a wide range of adiposity. Methods: We analyzed 10 641 subjects aged 20 to 59 years in National Health and Nutrition Examination Survey 2011-2018 who had undergone total body BMD and had VAT and SAT measured by dual-energy X-ray absorptiometry. Linear regression models were fitted while controlling for age, sex, race or ethnicity, smoking status, height, and lean mass index. Results: In a fully adjusted model, each higher quartile of VAT was associated with an average of 0.22 lower T-score (95% CI, -0.26 to -0.17, Conclusions: VAT has a negative association with BMD. Further research is needed to better understand the mechanism of action and, more generally, to develop strategies for optimizing bone health in obese subjects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.