Evidence map›Paper›PMID 36793451›Full record

ArticleInternational journal of Alzheimer's disease2023

CSF-Targeted Proteomics Indicate Amyloid-Beta Ratios in Patients with Alzheimer's Dementia Spectrum.

Maryam Behzad, Negin Zirak, Ghazal Hamidi Madani, Linda Baidoo, Ali Rezaei, Shima Karbasi, Mohammad Sadeghi, Mahan Shafie, Mahsa Mayeli, Alzheimer's Disease Neuroimaging Initiative

Registry-linked trialAbstract read
In one paragraph

Article in International journal of Alzheimer's disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00106899 (Alzheimer's Disease Neuroimaging Initiative), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00106899 completednot on this map

Alzheimer's Disease Neuroimaging Initiative

TypeobservationalSponsorAlzheimer's Disease Cooperative Study (ADCS)Ran2005 to 2011Enrolled818ConditionsAlzheimer's DiseaseArmsMagnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Lumbar Puncture (LP)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Biomarkers of cognitive and memory decline in psychotropic drug users.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Alcohol Use Disorder and Dementia: A Review.Alcohol research : current reviews · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maryam BehzadNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-4125-845X
Negin ZirakNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-5277-2139
Ghazal Hamidi MadaniNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-6131-0120
Linda BaidooNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ali RezaeiNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Shima KarbasiNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-8948-4210
Mohammad SadeghiNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mahan ShafieNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-3520-1553
Mahsa MayeliNeuroTRACT Association, Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4656-156X
Alzheimer's Disease Neuroimaging InitiativeAlzheimer's Disease Neuroimaging Initiative, USA.

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

Background: According to recent studies, amyloid- Methods: A total of 719 participants were found eligible for inclusion. Patients were then categorized into cognitively normal (CN), mild cognitive impairment (MCI), and AD and underwent an assessment of A Results: All investigated peptides corresponded significantly to A Conclusion: Our research suggests potential early diagnostic and prognostic utilities for certain peptides extracted from CSF-targeted proteomics research. The ethical approval of ADNI is available at ClinicalTrials.gov with Identifier: NCT00106899.

Identifiers

PMID36793451
PMCPMC9925239

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.