Evidence map›Paper›PMID 36793432›Full record

ArticleACS medicinal chemistry letters2023

Squaramide Tethered Clindamycin, Chloroquine, and Mortiamide Hybrids: Design, Synthesis, and Antimalarial Activity.

Thomas Tremblay, Catherine Bergeron, Dominic Gagnon, Christopher Bérubé, Normand Voyer, Dave Richard, Denis Giguère

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
  6. Synthesis of Azuleno[2,1-Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Thomas TremblayDépartement de Chimie, Université Laval, 1045 Av. de la Médecine, Québec City, QC G1V 0A6, Canada.
Catherine BergeronDépartement de Chimie, Université Laval, 1045 Av. de la Médecine, Québec City, QC G1V 0A6, Canada.
Dominic GagnonCentre de Recherche du CHU de Québec, Department of Microbiology, Infectious Diseases and Immunology, Faculty of Medicine, Université Laval, Québec City, QC G1V 0A6, Canada.
Christopher BérubéDépartement de Chimie, Université Laval, 1045 Av. de la Médecine, Québec City, QC G1V 0A6, Canada.
Normand VoyerDépartement de Chimie, Université Laval, 1045 Av. de la Médecine, Québec City, QC G1V 0A6, Canada.ORCID https://orcid.org/0000-0002-0429-9172
Dave RichardCentre de Recherche du CHU de Québec, Department of Microbiology, Infectious Diseases and Immunology, Faculty of Medicine, Université Laval, Québec City, QC G1V 0A6, Canada.
Denis GiguèreDépartement de Chimie, Université Laval, 1045 Av. de la Médecine, Québec City, QC G1V 0A6, Canada.ORCID https://orcid.org/0000-0003-2209-1428
Université Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria remains one of the major health problems in the world. In this work, a series of squaramide tethered chloroquine, clindamycin, and mortiamide D hybrids have been synthesized to assess their

Identifiers

PMID36793432
PMCPMC9923836
OpenAlexW4318040054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.