Evidence map›Paper›PMID 36793291›Full record

ArticleRSC advances2023

Biodegradable porous polymeric drug as a drug delivery system: alleviation of doxorubicin-induced cardiotoxicity

Qiuhong Jiao, Baoting Liu, Xiufeng Xu, Tao Huang, Bufan Cao, Lide Wang, Qingguo Wang, Ailing Du, Jingtian Li, Baolong Zhou and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Qiuhong JiaoDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Baoting LiuDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Xiufeng XuDepartment of Geriatrics, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China.
Tao HuangDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Bufan CaoDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Lide WangDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Qingguo WangDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Ailing DuDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Jingtian LiDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Baolong ZhouSchool of Pharmacy, Weifang Medical University Weifang 261031 Shandong China zhoubaolong@wfmc.edu.cn.ORCID https://orcid.org/0000-0001-7781-7842
Tao WangDepartment of Cardiology, Affiliated Hospital of Weifang Medical University Weifang 261031 Shandong China wfkljt@126.com wangtao575.happy@163.com.
Weifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin (DOX) is an effective chemotherapeutic drug developed against a broad range of cancers, and its clinical applications are greatly restricted by the side effects of severe cardiotoxicity during tumour treatment. Herein, the DOX-loaded biodegradable porous polymeric drug, namely, Fc-Ma-DOX, which was stable in the circulation, but easy to compose in the acidic medium, was used as the drug delivery system avoiding the indiscriminate release of DOX. Fc-Ma was constructed

Identifiers

PMID36793291
PMCPMC9923820
OpenAlexW4320491095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.