Evidence map›Paper›PMID 36793045›Full record

ArticleJournal of orthopaedic surgery and research2023

Early fusion outcome after surgical treatment of single-level and multi-level pyogenic spondylodiscitis: experience at a level 1 center for spinal surgery-a single center cohort study.

Motaz Hamed, Simon Brandecker, Tim Lampmann, Harun Asoglu, Abdallah Salemdawod, Erdem Güresir, Hartmut Vatter, Mohammed Banat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Motaz HamedDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Simon BrandeckerDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Tim LampmannDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Harun AsogluDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Abdallah SalemdawodDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Erdem GüresirDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Hartmut VatterDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany.
Mohammed BanatDepartment of Neurosurgery, University Hospital of Bonn, Venusberg-Campus 1, Building 81, 53127, Bonn, Germany. Mohammed.Banat@ukbonn.de.ORCID http://orcid.org/0000-0001-7986-5215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective single center cohort study. PURPOSE: Spinal instrumentation in combination with antibiotic therapy is a treatment option for acute or chronic pyogenic spondylodiscitis (PSD). This study compares the early fusion outcome for multi-level and single-level PSD after urgent surgical treatment with interbody fusion in combination with fixation.

methodsThis is a retrospective cohort study. Over a 10 year period at a single institution, all surgically treated patients received surgical debridement, fusion und fixation of the spine to treat PSD. Multi-level cases were either adjacent to each other on the spine or distant. Fusion rates were assessed at 3 and 12 months after surgery. We analyzed demographic data, ASA status, duration of surgery, location and length of spine affected, Charlson comorbidity index (CCI), and early complications.

resultsA total of 172 patients were included. Of these, 114 patients suffered from single-level and 58 from multi-level PSD. The most frequent location was the lumbar spine (54.0%) followed by the thoracic spine (18.0%). The PSD was adjacent in 19.0% and distant in 81.0% of multi-level cases. Fusion rates at the 3 month follow-up did not differ among the multi-level group (p = 0.27 for both adjacent and distant sites). In the single-level group, sufficient fusion was achieved in 70.2% of cases. Pathogen identification was possible 58.5% of the time.

conclusionsSurgical treatment of multi-level PSD is a safe option. Our study demonstrates that there was no significant difference in early fusion outcomes between single-level and multi-level PSD, whether adjacent or distant.

Indexed as

DiscitisSpinal FusionCohort StudiesDebridementHumansLumbar VertebraeRetrospective StudiesTreatment OutcomeIntervertebral fusion and instrumentationMulti-levelPyogenic spondylodiscitisSingle-levelSpinal instrumentationUrgent spinal surgery

Identifiers

PMID36793045
PMCPMC9930249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.