Evidence map›Paper›PMID 36792924›Full record

ArticleGlobal spine journal2024

Perioperative Complications Following Spine Surgery in Adult Patients with Achondroplasia.

Julie L Chan, Miguel D Quintero-Consuegra, Linda E A Kanim, Michael A Kropf, Robert Bernstein, Tiffany G Perry, Corey T Walker, Moise Danielpour, Alexander Tuchman

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Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Julie L ChanDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0002-0782-6548
Miguel D Quintero-ConsuegraDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Linda E A KanimDepartment of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Michael A KropfDepartment of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Robert BernsteinDepartment of Orthopaedic Surgery, Shriners Hospitals for Children Portland, Portland, OR, USA.
Tiffany G PerryDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Corey T WalkerDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Moise DanielpourDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Alexander TuchmanDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectivesTo describe the common types of complications and their risk factors during spine surgery in patients with achondroplasia.

methodsA retrospective review was performed of medical records of adult achondroplasia patients who underwent spine surgery at our institution between 2007 and 2021. Inclusion criteria were achondroplasia and age >16 years. Surgical encounters were evaluated for durotomy, postoperative neurologic deficit, wound compromise, medical complications, and return to the operating room. Statistical analysis included evaluation of relationships across complications and fisher exact test applied to bivariate/categorical variables and t-test/ANOVA for continuous variables. Multivariable analysis using logistic regression was performed to account for patient characteristics.

resultsFifty-five patients with achondroplasia underwent 95 surgeries. Forty-nine percent of the surgeries involved a complication. These included durotomy (33.7%), neurologic deficit (11.6%), wound compromise (6.3%), and other medical complications (6.3%). Thirteen percent of surgeries required return to the operating room. The greatest number of complications occurred in thoracolumbar region (60.0%) compared to cervicothoracic (18.2%) and craniocervical junction (33.3%). Chronologically later surgical encounters had decreased complications and durotomies only occurred in thoracolumbar surgeries (45.7%).

conclusionsAdult patients with achondroplasia undergoing surgery chronologically later in this set of consecutive patients were at a decreased risk for complications. Thoracolumbar surgeries were at the greatest risk for durotomies. Male sex was a risk factor for durotomy, while age was a risk factor for neurologic deficit. The potential for adverse surgical events should be considered when evaluating patients with achondroplasia for spine surgery. .

Indexed as

achondroplasiacomplicationsspine surgery

Identifiers

PMID36792924
PMCPMC11268303

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