Evidence map›Paper›PMID 36792875›Full record

ArticleAdvances in experimental medicine and biology2023

Role of Bacteriophages in the Evolution of Pathogenic Vibrios and Lessons for Phage Therapy.

Roberto C Molina-Quiroz, Andrew Camilli, Cecilia A Silva-Valenzuela

Abstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. First EuropeanBiology · 2024
    Article
  6. mBio · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roberto C Molina-QuirozStuart B. Levy Center for Integrated Management of Antimicrobial Resistance (Levy CIMAR), Tufts Medical Center and Tufts University, Boston, MA, USA.
Andrew CamilliDepartment of Molecular Biology and Microbiology, Tufts University, School of Medicine, Boston, MA, USA.
Cecilia A Silva-ValenzuelaMicrobes Lab SpA, Valdivia, Los Ríos, Chile. cecilia@microbes-lab.com.

Funding

Study of transmissible forms of Vibrio CholeraeR01AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI CAMILLI, ANDREW · 2003 to 2019
$5.8M
Phage Resistance in Emergent Vibrio cholerae and Phage Prophylaxis of CholeraR37AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI Andrew Camilli · 2020 to 2026
$3.4M
Mechanisms of Phage Predation on Environmental Vibrio choleraeR21AI147658 · NIAID · TUFTS UNIVERSITY BOSTON · PI CAMILLI, ANDREW · 2019 to 2020
$452k
NIAID NIH HHS R01 AI055058NIAID NIH HHS R21 AI147658NIAID NIH HHS R37 AI055058
6 · The paper itself

Abstract

Viruses of bacteria, i.e., bacteriophages (or phages for short), were discovered over a century ago and have played a major role as a model system for the establishment of the fields of microbial genetics and molecular biology. Despite the relative simplicity of phages, microbiologists are continually discovering new aspects of their biology including mechanisms for battling host defenses. In turn, novel mechanisms of host defense against phages are being discovered at a rapid clip. A deeper understanding of the arms race between bacteria and phages will continue to reveal novel molecular mechanisms and will be important for the rational design of phage-based prophylaxis and therapies to prevent and treat bacterial infections, respectively. Here we delve into the molecular interactions of Vibrio species and phages.

Indexed as

BacteriophagesPhage TherapyVibrioBacteriophagesPhage therapyVibrio choleraeVibrio evolution

Identifiers

PMID36792875
PMCPMC10587905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.