Evidence map›Paper›PMID 36792870›Full record

ArticleAdvances in experimental medicine and biology2023

Type VI Secretion Systems: Environmental and Intra-host Competition of Vibrio cholerae.

Francis Santoriello, Stefan Pukatzki

Abstract read
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In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francis SantorielloDepartment of Biology, The City College of New York, New York, NY, USA.
Stefan PukatzkiDepartment of Biology, The City College of New York, New York, NY, USA. spukatzki@ccny.cuny.edu.
City College of New York · US

Funding

The Role of Type VI Secretion in Cholera PathogenesisR01AI139103 · NIAID · UNIVERSITY OF COLORADO DENVER · PI PUKATZKI, STEFAN · 2019 to 2023
$4.2M
NIAID NIH HHS R01 AI139103
6 · The paper itself

Abstract

The Vibrio Type VI Secretion System (T6SS) is a harpoon-like nanomachine that serves as a defense system and is encoded by approximately 25% of all gram-negative bacteria. In this chapter, we describe the structure of the T6SS in different Vibrio species and outline how the use of different T6SS effector and immunity proteins control kin selection. We summarize the genetic loci that encode the structural elements that make up the Vibrio T6SSs and how these gene clusters are regulated. Finally, we provide insights into T6SS-based competitive dynamics, the role of T6SS genetic exchange in those competitive dynamics, and roles for the Vibrio T6SS in virulence.

Indexed as

Type VI Secretion SystemsVibrio choleraeBacterial ProteinsVirulenceBacterial ProteinsType VI Secretion SystemsBacterial competitionType VI secretion systemVibrio cholerae

Identifiers

PMID36792870
OpenAlexW4320903268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.