Evidence map›Paper›PMID 36792806›Full record

ArticleScientific reports2023

A proof of principle study using radiopharmaceuticals to quantify and localize container-content interactions in medical syringes.

C Dupire, P Chennell, B Pereira, N Courtiol, S Buj, R Cueff, S Crauste-Manciet, V Sautou, C Morgat

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Quality and pratical determinants in [EJNMMI radiopharmacy and chemistry · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C Dupire *Pharmaceutical Technology Department, Bordeaux University Hospital, Bordeaux, France.
P Chennell *Université Clermont Auvergne, CHU Clermont Ferrand, Clermont Auvergne INP, CNRS, ICCF, 63000, Clermont-Ferrand, France.
B PereiraDepartment of Clinical Research and Innovation, Clermont-Ferrand University Hospital, Clermont-Ferrand, France.
N CourtiolPharmaceutical Technology Department, Bordeaux University Hospital, Bordeaux, France.
S BujNuclear Medicine Department, Bordeaux University Hospital, Bordeaux, France.
R CueffUniversité Clermont Auvergne, Clermont Auvergne INP, CNRS, ICCF, 63000, Clermont-Ferrand, France.
S Crauste-MancietMINT Laboratory UMR INSERM 1066/CNRS 6021, IBS CHU, 4 Rue Larrey, 49933, Angers Cedex 9, France.
V SautouUniversité Clermont Auvergne, CHU Clermont Ferrand, Clermont Auvergne INP, CNRS, ICCF, 63000, Clermont-Ferrand, France.
C MorgatNuclear Medicine Department, Bordeaux University Hospital, Bordeaux, France. clement.morgat@chu-bordeaux.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sorption of drugs onto their contents is a known phenomenon that is difficult to analyse precisely. The purpose of this study was to present a non-invasive method for locating and quantifying sorption phenomena using radiopharmaceuticals. Radiopharmaceutical are medicines armed with a radionuclide enabling quantification and imaging using dedicated scanners. The sorption of nine different radiopharmaceuticals on 2- and 3-part syringes was investigated. These syringes were filled with the studied radiopharmaceutical solutions and stored immobile for 3 h. At different times ranging from 0 to 180 min, 10 µL were taken from the syringes and the radioactivity of these samples was determined by a gamma counter. 5 radiopharmaceuticals exhibited no significant sorption at any time point in both 2 and 3-parts syringes, but 4 radiopharmaceuticals exhibited sorption losses varying from 20 to 33% after 3 h contact with 3-part-syringes, but no sorption on 2-part syringes at any time point. [

Indexed as

RadiopharmaceuticalsSyringesRubberRadiopharmaceuticalsRubber

Identifiers

PMID36792806
PMCPMC9932089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.