Evidence map›Paper›PMID 36792792›Full record

ArticleScientific reports2023

Cross-municipality migration and spread of tuberculosis in South Africa.

Abdou M Fofana, Harry Moultrie, Lesley Scott, Karen R Jacobson, Anne N Shapiro, Graeme Dor, Beth Crankshaw, Pedro Da Silva, Helen E Jenkins, Jacob Bor and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Abdou M FofanaInstitute for Health System Innovation & Policy, Boston University, Questrom School of Business, Boston, USA. afofana@bu.edu.
Harry MoultrieCentre for Tuberculosis, National Institute for Communicable Diseases, a division of the National Health Laboratory Services, Johannesburg, South Africa.
Lesley ScottWits Diagnostic Innovation Hub, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Karen R JacobsonSection of Infectious Diseases, Boston University School of Medicine and Boston Medical Center, Boston, USA.
Anne N ShapiroBoston University School of Public Health, Boston, USA.
Graeme DorWits Diagnostic Innovation Hub, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Beth CrankshawCentre for Tuberculosis, National Institute for Communicable Diseases, a division of the National Health Laboratory Services, Johannesburg, South Africa.
Pedro Da SilvaNational Health Laboratory Service, Johannesburg, South Africa.
Helen E JenkinsBoston University School of Public Health, Boston, USA.
Jacob BorHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Wendy S StevensWits Diagnostic Innovation Hub, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Boston University · USNational Health Laboratory Service · ZAUniversity of the Witwatersrand · ZA

Funding

Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)R01AI147316 · NIAID · BOSTON MEDICAL CENTER · PI JACOBSON, KAREN R · 2019 to 2023
$3.5M
Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohortR01AI152126 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI JENKINS, HELEN E., SCOTT, LESLEY · 2020 to 2024
$1.6M
NIAID NIH HHS R01 AI147316NIAID NIH HHS R01 AI152126
6 · The paper itself

Abstract

Human migration facilitates the spread of infectious disease. However, little is known about the contribution of migration to the spread of tuberculosis in South Africa. We analyzed longitudinal data on all tuberculosis test results recorded by South Africa's National Health Laboratory Service (NHLS), January 2011-July 2017, alongside municipality-level migration flows estimated from the 2016 South African Community Survey. We first assessed migration patterns in people with laboratory-diagnosed tuberculosis and analyzed demographic predictors. We then quantified the impact of cross-municipality migration on tuberculosis incidence in municipality-level regression models. The NHLS database included 921,888 patients with multiple clinic visits with TB tests. Of these, 147,513 (16%) had tests in different municipalities. The median (IQR) distance travelled was 304 (163 to 536) km. Migration was most common at ages 20-39 years and rates were similar for men and women. In municipality-level regression models, each 1% increase in migration-adjusted tuberculosis prevalence was associated with a 0.47% (95% CI: 0.03% to 0.90%) increase in the incidence of drug-susceptible tuberculosis two years later, even after controlling for baseline prevalence. Similar results were found for rifampicin-resistant tuberculosis. Accounting for migration improved our ability to predict future incidence of tuberculosis.

Indexed as

HIV InfectionsTuberculosisTuberculosis, Multidrug-ResistantAdultCitiesFemaleHumansMaleSouth AfricaSurveys and QuestionnairesYoung Adult

Identifiers

PMID36792792
PMCPMC9930008
OpenAlexW4321002117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.