SynthesisSurgical endoscopy2023
Efficacy & safety of EUS-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE) in Roux-en-Y gastric bypass anatomy: a systematic review & meta-analysis.
Synthesis in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review of technical factors associated with persistent fistula after EUS-directed transgastric ERCP in patients with Roux-en-Y gastric bypass.Gastrointestinal endoscopy · 2025Pooled it
- Effectiveness and complication rates of percutaneous transhepatic fluoroscopy-guided management of common bile duct stones: a single-arm meta-analysis.European radiology · 2023Pooled it
- Current Evidence on Endoscopic Biliary Drainage in the Era of Surgically Altered Anatomy: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Weight matters: long-term evaluation of weight regain and fistula recurrence post endoscopic ultrasound-directed transgastric ERCP (EDGE).Surgical endoscopy · 2026Article
- International Consensus Statements on Endoscopic Ultrasound-Guided Biliary Drainage: Results From the 1st JGES International in 2025.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Article
- Common Bile Duct Access After Bariatric Surgery: A Narrative Review of Endoscopic Considerations for Treatment of Choledocholithiasis.Diagnostics (Basel, Switzerland) · 2026Review
- Therapeutic Endoscopic Ultrasound in Biliopancreatic Disease.Journal of clinical medicine · 2026Review
- Endoscopic Ultrasound-Guided Lumen-Apposing Metal Stent Drainage in Benign Pancreatobiliary and Gastrointestinal Disease: Evolving Techniques and Clinical Outcomes.Diagnostics (Basel, Switzerland) · 2026Review
- Intra-Procedural Real-Time Predictors of Failure in Patients with Roux-en-Y Gastric Bypass Undergoing Double-Balloon Assisted ERCP: Is There an Optimal Time to Cross-Over to EUS-Directed Transgastric ERCP? A Prospective Single-Center Study.Journal of clinical medicine · 2026Article
- Evaluation of time to endosonographic creation route after endoscopic ultrasound-guided hepaticogastrostomy.Endoscopy international open · 2026Article
- Endoscopic ultrasound-directed transenteric ERCP in patients with benign and malignant diseases and inaccessible biliary system.Endoscopy international open · 2026Article
- Endoscopic Ultrasound-Directed Transgastric Endoscopic Retrograde Cholangiopancreatography (EDGE): Techniques, Outcomes and Safety Profiles.Journal of clinical medicine · 2025Review
- Is endoscopic ultrasound-guided gastroenterostomy better than surgical gastrojejunostomy or duodenal stenting?Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Review
- Current status and further directions of endoscopic ultrasound-directed transgastric ERCP and endoscopic ultrasound-directed transenteric ERCP in the management of pancreaticobiliary diseases in surgically altered anatomy: a comprehensive review.Therapeutic advances in gastroenterology · 2025Review
- Article
- Biliary drainage in patients with malignant distal biliary obstruction: results of an Italian consensus conference.Surgical endoscopy · 2024Article
- Outcomes of lumen apposing metal stent placement in patients with surgically altered anatomy: Multicenter international experience.Endoscopy international open · 2024Article
- Endoscopic Management of Biliary and Pancreatic Pathologies in Roux-en-Y Gastric Bypass Patients: Development of a Treatment Algorithm Based on 9-Year Experience.Obesity surgery · 2024Article
- Primary anastomosis closure after endoscopic ultrasound-directed transgastric intervention.Endoscopy international open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn patients with Roux-en-Y gastric bypass (RYGB) anatomy, laparoscopic endoscopic retrograde cholangiopancreatography (LA-ERCP) and enteroscopy-assisted ERCP (E-ERCP) have been utilized to achieve pancreaticobiliary access. Endoscopic ultrasound-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE) has recently emerged as an alternate and efficient approach. As data regarding EDGE continues to evolve, concerns about safety and efficacy remain, limiting wide adoptability. We performed a systematic review and meta-analysis to assess the safety and efficacy of EDGE and compare it to the current standard of care.
methodsA comprehensive search of major databases (inception to Nov 2022) identified published studies on EDGE. A random-effects model was used to calculate the pooled rates and heterogeneity (I
resultsA total of 16 studies (470 patients) were included. EDGE pooled technical success (TS) rate was 96% (95% CI 92-97.6, I
conclusionOur analysis shows that EDGE is safe and efficacious to the current standard of care. Further head-to-head comparative trials are needed to validate our findings.
Indexed as
Identifiers
36792784What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.