Evidence map›Paper›PMID 36792362›Full record

ArticleeNeuro2023

Imaging Voltage Globally and in Isofrequency Lamina in Slices of Mouse Ventral Cochlear Nucleus.

Yihe Ma, Wen-Chi Shu, Lin Lin, Xiao-Jie Cao, Donata Oertel, Philip H Smith, Meyer B Jackson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yihe MaDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.
Wen-Chi ShuDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.
Lin LinDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.
Xiao-Jie CaoDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.
Donata OertelDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.ORCID https://orcid.org/0000-0001-8416-7470
Philip H SmithDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.
Meyer B JacksonDepartment of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705 meyer.jackson@wisc.edu.ORCID https://orcid.org/0000-0003-2904-7091
University of Wisconsin–Madison · US

Funding

Fusion pores in endocrine and synaptic exocytosisR35NS127219 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI MEYER B. JACKSON · 2022 to 2026
$4.7M
Plastic Synaptic Interconnections between Principal cells of the Ventral Cochlear NucleusR01DC016861 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI SMITH, PHILIP H · 2018 to 2022
$2.3M
Circuit Mechanisms of Information Processing and Storage in Brain SlicesR01NS093866 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI JACKSON, MEYER B. · 2015 to 2019
$1.6M
Task Specific Synaptic Connections in Auditory ProcessingR21DC014858 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI JACKSON, MEYER B., SUGDEN, DONATA OERTEL · 2015 to 2016
$412k
NIDCD NIH HHS R01 DC016861NIDCD NIH HHS R21 DC014858NINDS NIH HHS R01 NS093866NINDS NIH HHS R35 NS127219
6 · The paper itself

Abstract

The cochlear nuclei (CNs) receive sensory information from the ear and perform fundamental computations before relaying this information to higher processing centers. These computations are performed by distinct types of neurons interconnected in circuits dedicated to the specialized roles of the auditory system. In the present study, we explored the use of voltage imaging to investigate CN circuitry. We tested two approaches based on fundamentally different voltage sensing technologies. Using a voltage-sensitive dye we recorded glutamate receptor-independent signals arising predominantly from axons. The mean conduction velocity of these fibers of 0.27 m/s was rapid but in range with other unmyelinated axons. We then used a genetically-encoded hybrid voltage sensor (hVOS) to image voltage from a specific population of neurons. Probe expression was controlled using Cre recombinase linked to

Indexed as

Cochlear NucleusAnimalsAuditory PathwaysAuditory PerceptionAxonsHearingMiceNeuronsauditory nervec-foscochlear nucleigenetically-encoded voltage sensorstonotopic organizationvoltage imaging

Identifiers

PMID36792362
PMCPMC9997695
OpenAlexW4320896750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.