Evidence map›Paper›PMID 36792202›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Sporadic Myotonic Dystrophy Type 2 in a Japanese Patient.

Koichi Miyashita, Yuichiro Ii, Hirofumi Matsuyama, Atsushi Niwa, Yosuke Kawana, Soshi Shibata, Narihiro Minami, Ichizo Nishino, Hidekazu Tomimoto

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Koichi MiyashitaDepartment of Neurology, Mie University Graduate School of Medicine, Japan.
Yuichiro IiDepartment of Neurology, Mie University Graduate School of Medicine, Japan.
Hirofumi MatsuyamaDepartment of Neurology, Mie University Graduate School of Medicine, Japan.
Atsushi NiwaDepartment of Neurology, National Mie Hospital, Japan.
Yosuke KawanaDepartment of Neurology, Saiseikai Matsusaka General Hospital, Japan.
Soshi ShibataDepartment of Neurology, Suzuka Chuo General Hospital, Japan.
Narihiro MinamiDepartment of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, Japan.
Ichizo NishinoDepartment of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, Japan.
Hidekazu TomimotoDepartment of Neurology, Mie University Graduate School of Medicine, Japan.
Mie University · JPNational Center of Neurology and Psychiatry · JPNational Mie Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a Japanese patient with myotonic dystrophy type 2 (DM2), which is rare in Japan. A 64-year-oldman had proximal muscle weakness and grip myotonia. Electromyography showed myotonic discharges, but dystrophia-myotonica protein kinase (DMPK) was negative for CTG repeats. A muscle biopsy revealed increased central nuclei, pyknotic nuclear clumps and muscle fiber atrophy, mainly in type 2 fibers, raising the possibility of DM2. The diagnosis was genetically confirmed by the abnormal CCTG repeat size in cellular nucleic acid-binding protein (CNBP) on repeat-primed polymerase chain reaction, which was estimated to be around 4,500 repeats by Southern blotting.

Indexed as

Myotonic DystrophyEast Asian PeopleElectromyographyHumansMuscle WeaknessPolymerase Chain Reactiongene analysismuscle biopsymyotonic dystrophy type 2

Identifiers

PMID36792202
PMCPMC10641181
OpenAlexW4320718158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.