ArticleThe Journal of nutrition2023
A Practical Guide to Adjust Micronutrient Biomarkers for Inflammation Using the BRINDA Method.
Article in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 36 citations in OpenAlex.
- Impact of oral iron dosing regimens on iron biomarkers during pregnancy: insights from the PANDA trial.Blood advances · 2026Trial
- Energy restriction and iron supplementation improve iron status in women with obesity regardless of red meat consumption: a randomized controlled trial.Scientific reports · 2026Trial
- Effectiveness of intermittent iron and high-dose vitamin A supplementation on hemoglobin, iron and vitamin A status of schoolchildren in southern Ethiopia: a randomized placebo controlled trial.European journal of clinical nutrition · 2026Trial
- Women-led sustainable irrigation improved indicators of nutritional status in children from Northern Benin.Journal of health, population, and nutrition · 2025Trial
- Heme iron compared with ferrous iron salts to treat iron deficiency anemia in Gambian children: a randomized controlled trial.The American journal of clinical nutrition · 2025Trial
- Impacts of a Homestead Food Production Intervention on Anaemia and Micronutrient Deficiencies Among Women and Children in Rural Bangladesh: A Cluster-Randomized Controlled Trial.Maternal & child nutrition · 2025Trial
- Cortisol Stress Response is Associated with Iron Status in Pregnancy.medRxiv : the preprint server for health sciences · 2026Article
- Population-Level Changes in Folate, Iodine, and Vitamin D Status over More than 20 Years: Biomarker Data from the Cross-Sectional National Health and Nutrition Examination Survey (NHANES 1999-2000 through August 2021-August 2023).Current developments in nutrition · 2026Article
- The Prevalence of Nutritional Imbalances in the US Population Over Time: Biomarker Data from the Cross-Sectional National Health and Nutrition Examination Survey (NHANES 1999-2000 through August 2021-August 2023).Current developments in nutrition · 2026Article
- Saliva as a Matrix for Primary Care: Feasibility and Scoping of Its Use for Assessment of Nutrition and Inflammation.Advances in nutrition (Bethesda, Md.) · 2026Review
- Article
- Consumption of Selected Healthy and Unhealthy Food Groups and Associations With Nutritional Status Among Children 2-5 Years of Age in Northern Ghana.Maternal & child nutrition · 2026Article
- Vitamin A intake and status and associations with iron status, anaemia and birth outcomes of pregnant women in the Free State Province, South Africa: the Nutritional Status of Expectant Mothers and their newborn Infants (NuEMI) study.The British journal of nutrition · 2026Article
- Serum ferritin levels in a sample of older participants in the Greek HYDRIA survey: associations with sociodemographic and lifestyle parameters including dietary iron intake and Mediterranean diet score.The British journal of nutrition · 2026Article
- Iron status in women of reproductive age in Switzerland: the role of inflammation and ferritin thresholds for the prevalence of iron deficiency-a cross-sectional study.European journal of clinical nutrition · 2026Article
- Adjusting Iron Markers for Inflammation Reduces Misclassification of Iron Deficiency After Total Hip Arthroplasty.Journal of clinical medicine · 2025Article
- Silent losses: predictors of anaemia and micronutrient deficiencies and their associations with menstrual bleeding in Lebanon - findings from a national cross-sectional study.BMJ global health · 2025Article
- Revisiting the Obesity-Anaemia Paradox: Inflammation and Iron Homeostasis in the BMI-Haemoglobin Relationship.Endocrinology, diabetes & metabolism · 2025Article
- Vitamin A deficiency in India and seasonality of vitamin A-rich food consumption.The British journal of nutrition · 2025Article
- Malaria infection confounds inflammation-adjusted micronutrient biomarker concentrations in children and women in Malawi: a secondary analysis of the 2015/2016 Malawi micronutrient survey.The British journal of nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
Abstract
The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) research group was formed over a decade ago to improve the interpretation of micronutrient biomarkers in settings with inflammation. The BRINDA inflammation adjustment method uses regression correction to adjust for the confounding effects of inflammation on select micronutrient biomarkers and has provided important insights to micronutrient research, policy, and programming. However, users may face challenges when applying the BRINDA inflammation adjustment methods to their own data due to varying guidance on the adjustment approach for different biomarkers and the need to develop statistical programming to conduct these analyses. This may result in lost opportunities to have results of micronutrient data readily available during critical decision-making periods. Our research objectives are to 1) provide an all-in-one summary of the BRINDA method in adjusting multiple micronutrient biomarkers for inflammation, 2) evaluate whether malaria as a binary variable should be included in the BRINDA inflammation adjustment method, and 3) present standardized and user-friendly BRINDA adjustment R package and SAS macro. This paper serves as a practical guidebook for the BRINDA inflammation adjustment approach and aids users to use the BRINDA R package and SAS to streamline their analyses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.