Evidence map›Paper›PMID 36791255›Full record

ArticleAmerican journal of speech-language pathology2023

DementiaBank: Theoretical Rationale, Protocol, and Illustrative Analyses.

Alyssa M Lanzi, Anna K Saylor, Davida Fromm, Houjun Liu, Brian MacWhinney, Matthew L Cohen

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in American journal of speech-language pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07200739 (Development of Deep Learning Models for Detection of Neurodegenerative Diseases Using Speech - a Danish Language-based Artificial Intelligence Study), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07200739 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Development of Deep Learning Models for Detection of Neurodegenerative Diseases Using Speech - a Danish Language-based Artificial Intelligence Study (DetectAI)

TypeobservationalSponsorZealand University HospitalRan2026 to 2028Enrolled440ConditionsDementia (Diagnosis), Alzheimer Dementia (AD), Vascular Dementia (VaD), Lewy Body Dementia (LBD)ArmsMini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description, Speech Task - Picture Recall, MRI
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
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  3. Digital speech-based markers to advance prognosis in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  17. Developing digital health technologies for frontotemporal degeneration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  18. Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alyssa M LanziDepartment of Communication Sciences and Disorders, University of Delaware, Newark.ORCID 0000-0002-6460-9283
Anna K SaylorDepartment of Communication Sciences and Disorders, University of Delaware, Newark.ORCID 0000-0002-6327-8929
Davida FrommDepartment of Psychology, Carnegie Mellon University, Pittsburgh, PA.ORCID 0000-0002-4704-7709
Houjun LiuThe Nueva School, Hillsborough, CA.
Brian MacWhinneyDepartment of Psychology, Carnegie Mellon University, Pittsburgh, PA.ORCID 0000-0002-4988-1342
Matthew L CohenDepartment of Communication Sciences and Disorders, University of Delaware, Newark.ORCID 0000-0001-9609-2461
Google (United States) · US

Funding

RHDBank Database DevelopmentR01DC008524 · NIDCD · CARNEGIE-MELLON UNIVERSITY · PI BRIAN MACWHINNEY · 2007 to 2026
$7.0M
DementiaBank: An open access language database to understand the progression of dementiaRF1AG083823 · NIA · CARNEGIE-MELLON UNIVERSITY · PI LANZI, ALYSSA MARIE, MACWHINNEY, BRIAN · 2023 to 2023
$2.1M
Promoting Independence with Compensatory Cognitive Rehabilitation: A Pilot Clinical Trial for Early-Stage Alzheimer's DiseaseK23AG070185 · NIA · UNIVERSITY OF DELAWARE · PI LANZI, ALYSSA MARIE · 2021 to 2025
$870k
NIA NIH HHS K23 AG070185NIA NIH HHS RF1 AG083823NIDCD NIH HHS R01 DC008524
6 · The paper itself

Abstract

purposeDementia from Alzheimer's disease (AD) is characterized primarily by a significant decline in memory abilities; however, language abilities are also commonly affected and may precede the decline of other cognitive abilities. To study the progression of language, there is a need for open-access databases that can be used to build algorithms to produce translational models sensitive enough to detect early declines in language abilities. DementiaBank is an open-access repository of transcribed video/audio data from communicative interactions from people with dementia, mild cognitive impairment (MCI), and controls. The aims of this tutorial are to (a) describe the newly established standardized DementiaBank discourse protocol, (b) describe the Delaware corpus data, and (c) provide examples of automated linguistic analyses that can be conducted with the Delaware corpus data and describe additional DementiaBank resources.

methodThe DementiaBank discourse protocol elicits four types of discourse: picture description, story narrative, procedural, and personal narrative. The Delaware corpus currently includes data from 20 neurotypical adults and 33 adults with MCI from possible AD who completed the DementiaBank discourse protocol and a cognitive-linguistic battery. Language samples were video- and audio-recorded, transcribed, coded, and uploaded to DementiaBank. The protocol materials and transcription programs can be accessed for free via the DementiaBank website.

resultsIllustrative analyses show the potential of the Delaware corpus data to help understand discourse metrics at the individual and group levels. In addition, they highlight analyses that could be used across TalkBank's other clinical banks (e.g., AphasiaBank). Information is also included on manual and automatic speech recognition transcription methods.

conclusionsDementiaBank is a shared online database that can facilitate research efforts to address the gaps in knowledge about language changes associated with MCI and dementia from AD. Identifying early language markers could lead to improved assessment and treatment approaches for adults at risk for dementia.

Indexed as

Alzheimer DiseaseCognitive DysfunctionCognitionHumansLanguageLinguistics

Identifiers

PMID36791255
PMCPMC10171844
OpenAlexW4320896605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.