ArticleProceedings of the National Academy of Sciences of the United States of America2023
Soft, strong, tough, and durable protein-based fiber hydrogels.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- AI-powered the toughest biohydrogels.Bioactive materials · 2026Article
- Digital Printing of Photoreversible Protective Films.Macromolecular rapid communications · 2026Article
- Hydrogel-Based Systems in Intrauterine Adhesions: Bridging the Gap from Bench to Bedside.Advanced healthcare materials · 2026Review
- Ordered-Disorder Transition Induced Stretchable Collagen Ionic Gels Toward Flexible Sensors.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Architecting bioinspired nanocrystalline domains for ultimate robust and transparent cellulose photonic hydrogels.Science advances · 2026Article
- Programmable Semi-Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cell surface engineering with a pseudofibrotic ECM reprograms the antifibrotic activity of mesenchymal stromal cells.Science advances · 2026Article
- High-strength and fracture-resistant ionogels via solvent-tailored interphase cohesion in nanofibrous composite networks.Science advances · 2025Article
- Molecular Creep Induced Fatigue Rupture of Fibrin Clots.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Tailoring Self-Assembled Peptide Hydrogels with Antimicrobial or Cell Adhesive Properties for Tissue Engineering.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Overcoming ice: cutting-edge materials and advanced strategies for effective cryopreservation of biosample.Journal of nanobiotechnology · 2025Review
- Mussel-inspired cross-linking mechanisms enhance gelation and adhesion of multifunctional mucin-derived hydrogels.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Black Phosphorus Tagged Responsive Strontium Hydrogel Particles for Bone Defect Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A High-Density Hydrogen Bond Locking Strategy for Constructing Anisotropic High-Strength Hydrogel-Based Meniscus Substitute.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Anisotropic Liesegang pattern for the nonlinear elastic biomineral-hydrogel complex.Science advances · 2024Article
- 3D printing sequentially strengthening high-strength natural polymer hydrogel bilayer scaffold for cornea regeneration.Regenerative biomaterials · 2024Article
- Strategies for Development of Synthetic Heart Valve Tissue Engineering Scaffolds.Progress in materials science · 2023Article
- Hydrogel fibers for wearable sensors and soft actuators.iScience · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Load-bearing soft tissues normally show J-shaped stress-strain behaviors with high compliance at low strains yet high strength at high strains. They have high water content but are still tough and durable. By contrast, naturally derived hydrogels are weak and brittle. Although hydrogels prepared from synthetic polymers can be strong and tough, they do not have the desired bioactivity for emerging biomedical applications. Here, we present a thermomechanical approach to replicate the combinational properties of soft tissues in protein-based photocrosslinkable hydrogels. As a demonstration, we create a gelatin methacryloyl fiber hydrogel with soft tissue-like mechanical properties, such as low Young's modulus (0.1 to 0.3 MPa), high strength (1.1 ± 0.2 MPa), high toughness (9,100 ± 2,200 J/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.