Evidence map›Paper›PMID 36791051›Full record

ArticleJournal of neurophysiology2023

Biomarkers for rapid H-reflex operant conditioning among females.

Kristin A Johnson, Michael A Petrie, Richard K Shields

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kristin A JohnsonDepartment of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0002-7690-9777
Michael A PetrieDepartment of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0002-5212-0907
Richard K ShieldsDepartment of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0002-5838-9317
University of Iowa · US

Funding

Long Duration Activity and Metabolic Control after Spinal Cord InjuryR01HD082109 · NICHD · UNIVERSITY OF IOWA · PI SHIELDS, RICHARD K. · 2015 to 2019
$1.6M
Musculoskeletal Plasticity after Spinal Cord InjuryR01HD084645 · NICHD · UNIVERSITY OF IOWA · PI SHIELDS, RICHARD K. · 2015 to 2019
$1.6M
ACL HHS R49CE003095NCIPC CDC HHS R49 CE003095NICHD NIH HHS R01 HD082109NICHD NIH HHS R01 HD084645NIH HHS 5R01-HD082109-03NIH HHS 5R01-HD084645-12
6 · The paper itself

Abstract

Operant conditioning of a spinal monosynaptic pathway using the Hoffman reflex (H-reflex) is well established in animal and human studies. There is a subset within the human population (∼20% nonresponders) who are unable to up train this pathway suggesting some distinct or unique identifying characteristics. Importantly, females, who have a nine times higher rate of injury during human performance activities than men, have been understudied in areas of CNS neuroplasticity. Our long-term goal is to understand if innate ability to rapidly up train the H-reflex is predictive of future performance-based injury among females. In this study, we primarily determined whether healthy, young females could rapidly increase the H-reflex within a single session of operant conditioning and secondarily determined if electro-physiological, humoral, cognitive, anthropometric, or anxiety biomarkers distinguished the responders from nonresponders. Eighteen females (mean age: 24) participated in the study. Overall, females showed a group main effect for up training the H-reflex (

Indexed as

H-ReflexSpinal Cord InjuriesAdultAnimalsConditioning, OperantElectromyographyFemaleHumansMaleNeuronal PlasticityYoung AdultendocrineH-reflexlearningneuroplasticityoperant conditioning

Identifiers

PMID36791051
PMCPMC10010925
OpenAlexW4320856878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.