Evidence map›Paper›PMID 36790911›Full record

ArticleMolecular biology of the cell2023

Interrelated effects of chromosome size, mechanics, number, location-orientation and polar ejection force on the spindle accuracy: a 3D computational study.

Evgenii Kliuchnikov, Kenneth A Marx, Alexander Mogilner, Valeri Barsegov

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Optimal strategies for correcting merotelic chromosome attachments in anaphase.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Measuring and modeling the dynamics of mitotic error correction.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Evgenii KliuchnikovDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854.ORCID 0000-0002-2410-2138
Kenneth A MarxDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854.
Alexander MogilnerCourant Institute for Mathematical Sciences and Department of Biology, New York University, New York, NY 10012.
Valeri BarsegovDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854.
University of Massachusetts Lowell · USCourant Institute of Mathematical Sciences · US

Funding

Mechanisms of mechano-chemical rupture of blood clots and thrombiR01HL148227 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PUROHIT, PRASHANT KISHORE · 2020 to 2023
$2.5M
NHLBI NIH HHS R01 HL148227
6 · The paper itself

Abstract

The search-and-capture model of spindle assembly has been a guiding principle for understanding prometaphase for decades. The computational model presented allows one to address two questions: how rapidly the microtubule-kinetochore connections are made, and how accurate these connections are. In most previous numerical simulations, the model geometry was drastically simplified. Using the

Indexed as

CentromereChromosomesChromosome SegregationKinetochoresMicrotubulesMitosisPrometaphaseSpindle Apparatus

Identifiers

PMID36790911
PMCPMC10208101
OpenAlexW4320856450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.