Evidence map›Paper›PMID 36790804›Full record

ReviewReviews in medical virology2023

Respiratory infections and type 1 diabetes: Potential roles in pathogenesis.

Roy Wu, Mohsin Mumtaz, Anna J Maxwell, Sonia R Isaacs, Jutta E Laiho, William D Rawlinson, Heikki Hyöty, Maria E Craig, Ki Wook Kim

Open access · hybridAbstract readReview
In one paragraph

Review in Reviews in medical virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Roy WuDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.ORCID 0000-0003-0910-2399
Mohsin MumtazDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
Anna J MaxwellDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
Sonia R IsaacsDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
Jutta E LaihoDepartment of Virology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
William D RawlinsonDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.ORCID 0000-0003-0988-7827
Heikki HyötyDepartment of Virology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Maria E CraigDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.ORCID 0000-0001-6004-576X
Ki Wook KimDiscipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.ORCID 0000-0001-9579-6408
New South Wales Department of Health · AUTampere University of Applied Sciences · FIThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the environmental factors associated with type 1 diabetes (T1D), viral infections of the gut and pancreas has been investigated most intensely, identifying enterovirus infections as the prime candidate trigger of islet autoimmunity (IA) and T1D development. However, the association between respiratory tract infections (RTI) and IA/T1D is comparatively less known. While there are significant amounts of epidemiological evidence supporting the role of respiratory infections in T1D, there remains a paucity of data characterising infectious agents at the molecular level. This gap in the literature precludes the identification of the specific infectious agents driving the association between RTI and T1D. Furthermore, the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the development of IA/T1D remains undeciphered. Here, we provide a comprehensive overview of the evidence to date, implicating RTIs (viral and non-viral) as potential risk factors for IA/T1D.

Indexed as

COVID-19Diabetes Mellitus, Type 1Islets of LangerhansRespiratory Tract InfectionsHumansSARS-CoV-2autoimmunityrespiratory infectiontype 1 diabetesviromevirus

Identifiers

PMID36790804
PMCPMC10909571
OpenAlexW4320856065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.