Evidence map›Paper›PMID 36790675›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

Progress of gut microbiome and its metabolomics in early screening of colorectal cancer.

Lujia Zhou, Zhengting Jiang, Zhilin Zhang, Juan Xing, Daorong Wang, Dong Tang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Dysbiosis and colonic adenoma: The lethal link?World journal of clinical oncology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lujia Zhou *Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu Province, 225000, People's Republic of China.
Zhengting Jiang *Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu Province, 225000, People's Republic of China.
Zhilin ZhangClinical Medical College, Yangzhou University, Yangzhou, Jiangsu Province, 225000, People's Republic of China.
Juan XingClinical Medical College, Yangzhou University, Yangzhou, Jiangsu Province, 225000, People's Republic of China.
Daorong WangDepartment of General Surgery, Institute of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou, 225000, People's Republic of China.
Dong TangDepartment of General Surgery, Institute of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou, 225000, People's Republic of China. 83392785@qq.com.ORCID http://orcid.org/0000-0002-2057-2968
Yangzhou University · CNNorthern Jiangsu People's Hospital · CN

Funding

Graduate Research- Innovation Project in Jiangsu province SJCX21_1644High-level talent "six one projects" top talent scientific research project of Jiangsu Province LGY2019034Major Project of Philosophy and Social Science Research in Colleges and Universities of Jiangsu Province YZ2021075Social development project of key R & D plan of Jiangsu Provincial Department of science and technology BE2022773the Academic Science and Technology Innovation Fund for College Students 202011117056Ythe Graduate Research- Innovation Project in Jiangsu province SJCX22_1816
6 · The paper itself

Abstract

Gut microbes are widely considered to be closely associated with colorectal cancer (CRC) development. The microbiota is regarded as a potential identifier of CRC, as several studies have found great significant changes in CRC patients' microbiota and metabolic groups. Changes in microbiota, like Fusobacterium nucleatum and Bacteroides fragilis, also alter the metabolic activity of the host, promoting CRC development. In contrast, the metabolome is an intuitive discriminative biomarker as a small molecular bridge to distinguish CRC from healthy individuals due to the direct action of microbes on the host. More diagnostic microbial markers have been found, and the potential discriminatory power of microorganisms in CRC has been investigated through the combined use of biomic genomic metabolomics, bringing new ideas for screening fecal microbial markers. In this paper, we discuss the potential of microorganisms and their metabolites as biomarkers in CRC screening, hoping to provide thoughts and references for non-invasive screening of CRC.

Indexed as

Colorectal NeoplasmsGastrointestinal MicrobiomeMicrobiotaBiomarkersEarly Detection of CancerHumansMetabolomicsBiomarkersBiomarkerColorectal cancerMicrobiomeMulti-omicsScreening

Identifiers

PMID36790675
OpenAlexW4320856879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.