Evidence map›Paper›PMID 36790662›Full record

ArticleProbiotics and antimicrobial proteins2023

The Prevention Effect of Lactobacillus plantarum 17-5 on Escherichia coli-Induced Mastitis in Mice.

Ke Li, Ming Yang, Li Jia, Mengyue Tian, Jinliang Du, Yinghao Wu, Lining Yuan, Lianmin Li, Yuzhong Ma

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Evaluation ofFrontiers in veterinary science · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ke LiCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Ming YangCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Li JiaCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Mengyue TianCollege of Life Science and Food Engineering, Hebei University of Engineering, Handan, 056038, Hebei, China.
Jinliang DuCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Yinghao WuCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Lining YuanCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Lianmin LiCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China.
Yuzhong MaCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, 071001, Hebei, China. dkma@hebau.edu.cn.
Hebei Agricultural University · CNHebei University of Engineering · CN

Funding

Hebei Key Research and Development Program 19226611D
6 · The paper itself

Abstract

Mastitis is the most economically important disease affecting the dairy industry worldwide. Lactobacillus plantarum, an important probiotic with a wide range of applications, has potential anti-inflammatory properties and has become a currently strong candidate for mastitis therapies. In the current study, we evaluated the prevention effect of Lactobacillus plantarum 17-5 on Escherichia coli-induced mastitis in mice. The results showed that pretreatment with L. plantarum 17-5 maintained the integrity of tight junctions; improved inflammatory injury; decreased MPO activity and the mRNA expression levels of IL1β, IL6, and TNFα; and inhibited the NF-κB and MAPK signaling pathways in mice mammary tissue. The results indicated that Lactobacillus plantarum 17-5 had excellent anti-inflammatory activities and could be developed into microecological preparation for clinical use to prevent mastitis.

Indexed as

Lactiplantibacillus plantarumMastitisProbioticsAnimalsAnti-Inflammatory AgentsEscherichia coliFemaleHumansMiceNF-kappa BAnti-Inflammatory AgentsNF-kappa BEscherichia coliInflammationLactobacillus plantarumMAPKMastitisNF-κBTight junction

Identifiers

PMID36790662
OpenAlexW4320857899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.