Evidence map›Paper›PMID 36790616›Full record

ReviewCurrent microbiology2023

Juxtaposing Caenorhabditis elegans-Pathogenic Mould Model with Other Models; How Reliable Is This Nematode Model? A Mini Review.

Chukwuemeka Samson Ahamefule, Blessing C Ahamefule, Anthony C Ike, James C Ogbonna, Anene N Moneke

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chukwuemeka Samson AhamefuleDepartment of Microbiology, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria. chukwuemeka.ahamefule@unn.edu.ng.ORCID http://orcid.org/0000-0001-7374-1641
Blessing C AhamefuleDepartment of Microbiology, University of Jos, Jos, 930001, Plateau State, Nigeria.
Anthony C IkeDepartment of Microbiology, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
James C OgbonnaDepartment of Microbiology, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Anene N MonekeDepartment of Microbiology, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of Caenorhabditis elegans as a pathogenic model has spanned decades. Its use for pathogenic mould modeling has been attracting some attention lately, though not without some reservations. Several studies have shown C. elegans to be a reliable model for evaluating moulds' virulence factors and patterns as well as for screening the pathogenicity of mutant strains alongside their parental/wild type and revertant/complementary strains. There is a very high degree of reported similarities between the virulence patterns demonstrated in C. elegans and those of other invertebrate and vertebrate models. We have here presented several works in which this nematode model was adopted for virulence evaluation, and other comparative research in which virulence in C. elegans model were juxtaposed with other models. We have further presented possible reasons why there might have been variations of virulence in a few cases, thereby validating C. elegans to be an effective and reliable tool in the study of pathogenic moulds.

Indexed as

Caenorhabditis elegansNematodaAnimalsVirulenceVirulence FactorsVirulence Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.