Evidence map›Paper›PMID 36790401›Full record

ArticleMicrobiology (Reading, England)2023

Cross-species activation of hydrogen cyanide production by a promiscuous quorum-sensing receptor promotes

Cheyenne Loo, Pratik Koirala, Nathan C Smith, Kara C Evans, Saida Benomar, Isabelle R Parisi, Anna Oller, Josephine R Chandler

Open access · diamondAbstract read
In one paragraph

Article in Microbiology (Reading, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. A cytochromeApplied and environmental microbiology · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cheyenne LooDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Pratik KoiralaDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Nathan C SmithDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Kara C EvansDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Saida BenomarDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Isabelle R ParisiDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Anna OllerDepartment of Biological and Clinical Sciences, University of Central Missouri, Warrensburg, MO 64093, USA.
Josephine R ChandlerDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
University of Kansas · USStowers Institute for Medical Research · USUniversity of Central Missouri · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Synthetic Chemical Biology CoreP20GM113117 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OROZCO, ROBIN C. · 2016 to 2025
$23.9M
Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LUNTE, SUSAN M · 2012 to 2021
$22.1M
TRAINING GRANT IN DYNAMIC ASPECTS OF CHEMICAL BIOLOGYT32GM008545 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LAMB, AUDREY L · 1994 to 2019
$4.9M
Quorum sensing evolution and function in mixed bacterial communitiesR35GM133572 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI CHANDLER, JOSEPHINE R · 2019 to 2024
$2.1M
NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM103638NIGMS NIH HHS P20 GM113117NIGMS NIH HHS R35 GM133572NIGMS NIH HHS T32 GM008545
6 · The paper itself

Abstract

Many saprophytic bacteria have LuxR-I-type acyl-homoserine lactone (AHL) quorum-sensing systems that may be important for competing with other bacteria in complex soil communities. LuxR AHL receptors specifically interact with cognate AHLs to cause changes in expression of target genes. Some LuxR-type AHL receptors have relaxed specificity and are responsive to non-cognate AHLs. These promiscuous receptors might be used to sense and respond to AHLs produced by other bacteria by eavesdropping. We are interested in understanding the role of eavesdropping during interspecies competition. The soil saprophyte

Indexed as

Hydrogen CyanideQuorum SensingAcyl-ButyrolactonesChromobacteriumCyanidesTrans-ActivatorsAcyl-ButyrolactonesCyanidesHydrogen CyanideTrans-ActivatorsantibioticChromobacteriumcoculturecompetitioncyanidequorum sensing

Identifiers

PMID36790401
PMCPMC10197875
OpenAlexW4320857730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.